Cancer stem cells: advances in knowledge and implications for cancer therapy
X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Musashi RNA-binding proteins as cancer drivers and novel therapeutic targets
Aberrant gene expression that drives human cancer can arise from epigenetic
dysregulation. Although much attention has focused on altered activity of transcription …
dysregulation. Although much attention has focused on altered activity of transcription …
The Neural RNA-Binding Protein Musashi1 Translationally Regulates Mammalian numb Gene Expression by Interacting with Its mRNA
T Imai, A Tokunaga, T Yoshida… - … and cellular biology, 2001 - Taylor & Francis
Musashi1 (Msi1) is an RNA-binding protein that is highly expressed in neural progenitor
cells, including neural stem cells. In this study, the RNA-binding sequences for Msi1 were …
cells, including neural stem cells. In this study, the RNA-binding sequences for Msi1 were …
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells
In situ detection of neural progenitor cells including stem-like cells is essential for studying
the basic mechanisms of the generation of cellular diversity in the CNS, upon which …
the basic mechanisms of the generation of cellular diversity in the CNS, upon which …
Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana
ZJ Lorković, A Barta - Nucleic acids research, 2002 - academic.oup.com
Regulation of gene expression at the post-transcriptional level is mainly achieved by
proteins containing well-defined sequence motifs involved in RNA binding. The most widely …
proteins containing well-defined sequence motifs involved in RNA binding. The most widely …
Function of RNA-binding protein Musashi-1 in stem cells
Musashi is an evolutionarily conserved family of RNA-binding proteins that is preferentially
expressed in the nervous system. The first member of the Musashi family was identified in …
expressed in the nervous system. The first member of the Musashi family was identified in …
RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
M Montalbano, S McAllen, N Puangmalai… - Nature …, 2020 - nature.com
Oligomeric assemblies of tau and the RNA-binding proteins (RBPs) Musashi (MSI) are
reported in Alzheimer's disease (AD). However, the role of MSI and tau interaction in their …
reported in Alzheimer's disease (AD). However, the role of MSI and tau interaction in their …
Musashi: a translational regulator of cell fate
Transcription is thought to have a major role in the regulation of cell fate; the importance of
translational regulation in this process has been less certain. Recent findings demonstrate …
translational regulation in this process has been less certain. Recent findings demonstrate …
Stem cell biology of the central nervous system
H Okano - Journal of neuroscience research, 2002 - Wiley Online Library
Neural stem cells (NSCs) are multipotential progenitor cells that have self‐renewal activities.
A single NSC is capable of generating various kinds of cells within the central nervous …
A single NSC is capable of generating various kinds of cells within the central nervous …
Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS
S Sakakibara, Y Nakamura, H Satoh… - Journal of …, 2001 - Soc Neuroscience
Musashi1 (Msi1) is a mammalian neural RNA-binding protein highly enriched in neural
precursor cells that are capable of generating both neurons and glia during embryonic and …
precursor cells that are capable of generating both neurons and glia during embryonic and …