Abstract The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been
established to develop a public resource of genetic regulatory variants in livestock, which is …

Pigs are valuable large animal models for biomedical and genetic research, but insights into
the tissue-and cell-type-specific transcriptome and heterogeneity remain limited. By …

Intraepithelial lymphocytes (IELs) include T cells and innate lymphoid cells that are
important mediators of intestinal immunity and barrier defense, yet most knowledge of IELs …

Bats harbor high-impact zoonotic viruses often in the absence of disease manifestation. This
restriction and disease tolerance possibly rely on specific immunological features. In-depth …

Vaccination is the most effective medical strategy for disease prevention but there is a need
to improve livestock vaccine efficacy. Understanding the structure of the immune system of …

Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte
function is challenging as the intestine contains a vastly heterogeneous mixture of cells. Pigs …

Pig-to-human xenotransplantation is rapidly approaching the clinical arena; however, it is
unclear which immunomodulatory regimens will effectively control human immune …

Using an adult female miniature pig model with diet-induced weight gain/weight loss, we
investigated the regulatory mechanisms of three-dimensional (3D) genome architecture in …

Background Maternal air pollutants exposure is associated with a number of adverse
pregnancy outcomes, including recurrent spontaneous abortion (RSA). However, the …

The pig is a natural host for influenza viruses and integrally involved in virus evolution
through interspecies transmissions between humans and swine. Swine have many …