ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …

The demand for environmental friendly methodologies had shifted the the approach of
scientific community for using easy and green reaction conditions instead of using …

ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …

A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was
successfully synthesized, characterized, and evaluated for their antimicrobial responses …

Two libraries of biologically essential and fluorescent 7-azaindole N-linked benzyl 1, 2, 3-
triazole (4a–4i) and 7-azaindole N-linked phenyl 1, 2, 3-triazole (4j–4q) hybrids have been …

The anthropogenic influence on the environment, exemplified by phenomena such as global
warming, ozone layer depletion, glacier melting, biodiversity loss, and significant shifts in …

We report herein a new 1, 2, 3-triazole derivative, namely, 4-((1-(3, 4-dichlorophenyl)-1 H-1,
2, 3-triazol-4-yl) methoxy)-2-hydroxybenzaldehyde, which was synthesized by copper (I) …

Biothiols (cysteine, homocysteine, and glutathione) are an important class of compounds
with a free thiol group. These biothiols plays an important role in several metabolic …

To discover anticancer drugs with novel structures and expand our research scope,
pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of …

Background: This research aims to discover novel derivatives having potential therapeutic
applications in treating conditions related to prolyl oligopeptidase (POP) dysfunction …