Abstract BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international
endorsement as the standard biomarkers for detection of myocardial injury, for risk …

Circulation is available at http://www. circulationaha. org DOI: 10.1161/CIRCULATIONAHA.
107.182881 e352 were to recommend the appropriate implementation and utilization of …

The first account of the use of a biochemical marker in the study of myocardial injury was
published by La Due and colleagues in the journal Science in 1954. 85 They measured …

Background: Protein biomarker candidates from discovery proteomics must be quantitatively
verified in patient samples before they can progress to clinical validation. Here we …

Heart diseases, especially coronary artery diseases (CAD), are the leading causes of
morbidity and mortality in developed countries. Effective therapy is available to ensure …

BACKGROUND OF THE EWG The Expert Working Group (EWG) on Biomarkers of Drug-
Induced Cardiac Toxicity was established as a factfinding working group to the Nonclinical …

Background The European Society of Cardiology and American College of Cardiology
guidelines for redefinition of myocardial infarction suggest that the cutoff value for diagnosis …

Implementation of cardiac troponin (cTn) assays has revolutionized the diagnosis, risk
stratification, triage and management of patients with suspected myocardial infarction (MI) …

This new edition of Basic Skills in Interpreting Laboratory Data, 4th Edition is acase-based
learning tool that will enhance your skills in clinical lab test interpretation. It provides …

Cardiac troponin T (cTnT) and I (cTnI) are highly specific and sensitive biomarkers of
myocardial cell damage and are now accepted as the 'gold standard'diagnostic test for acute …