Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …

Many pharmaceutically active molecules are highly lipophilic, which renders their
administration and adsorption in patients extremely challenging. Among the countless …

Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the
best features of ideal drug carriers necessary for improving the oral absorption and …

Cancer is one of the leading causes of morbidity and mortality around the globe and is likely
to become the major cause of global death in the coming years. As per World Health …

The delivery of drugs via fast dissolving films is an effective alternative for drugs with low
bioavailability when administered by other routes. This is the case of domperidone (DMP) an …

The purpose of this work was to evaluate solid lipid nanoparticles (SLNs) as a long acting
injectable drug delivery platform for intramuscular and subcutaneous administration. SLNs …

Background The poor palatability, variable oral bioavailability, stimulation to gastric mucosa,
and light instability limited the application of enrofloxacin (ENR). The enteric granules …

Introduction This study aimed to prepare cholesterol and stearic acid-based solid lipid
nanoparticles of gabapentin (GAB-SLNs) for protection against streptozotocin (STZ)-induced …

Objective The main scope of the present investigation was to improve the bioavailability of
perphenazine (PPZ) by incorporating it into the nanostructured lipid carriers (NLCs) …