Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of
research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide …

In the present update on mucoadhesive ocular dosage forms, the tremendous advances in
the biochemistry of mucins, the development of new polymers, the use of drug complexes …

Eye diseases and injuries impose a significant clinical problem worldwide. Safe and
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …

Dry eye disease (DED) is a growing public health concern affecting quality of life and visual
function, with a significant socio-economic impact. It is characterised by the loss of …

Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG), cell-
surface-associated biopolymer and is the key component of tissue extracellular matrix …

Dry eye disease (DED) is a highly prevalent and debilitating condition affecting several
hundred million people worldwide. Hyaluronic acid (HA) is a naturally occurring …

Objectives: Ocular surface disease frequently coexists with glaucoma and may be initiated
or exacerbated by topical glaucoma medications. We performed a review of current literature …

Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

• Mild chronic renal compromise34 continued association with antibodies against
neuropeptides. 42 Increased rates of neuroticism, psychoticism, obsessiveness …

Purpose: Sodium hyaluronate (hyaluronic acid) is known to promote corneal epithelial
wound healing in vivo and in vitro, in animal experiments. Sodium hyaluronate is the ligand …