[HTML][HTML] Hallmarks of regeneration

KD Poss, EM Tanaka - Cell stem cell, 2024 - cell.com
Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

[HTML][HTML] Marvels of spiny mouse regeneration: cellular players and their interactions in restoring tissue architecture in mammals

A Tomasso, V Disela, MT Longaker… - Current Opinion in …, 2024 - Elsevier
Understanding the cellular and molecular determinants of mammalian tissue regeneration
and repair is crucial for developing effective therapies that restore tissue architecture and …

The sea spider Pycnogonum litorale overturns the paradigm of the absence of axial regeneration in molting animals

G Brenneis, K Frankowski, L Maaß… - Proceedings of the …, 2023 - National Acad Sciences
Regenerative abilities and their evolution in the different animal lineages have fascinated
generations of biologists. While some taxa are capable of restoring entire individuals from …

Spiny mice are primed but fail to regenerate volumetric skeletal muscle loss injuries

ML Davenport, A Fong, KN Albury, CS Henley-Beasley… - Skeletal Muscle, 2024 - Springer
Background In recent years, the African spiny mouse Acomys cahirinus has been shown to
regenerate a remarkable array of severe internal and external injuries in the absence of a …

Integration failure of regenerated limb tissue is associated with incongruencies in positional information in the Mexican axolotl

WA Vieira, M Raymond, K Kelley… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Little is known about how the newly regenerated limb tissues in the Mexican
axolotl seamlessly integrate with the remaining stump tissues to form a functional structure …

[HTML][HTML] Nature's Secret Neuro-Regeneration Pathway in Axolotls, Polychaetes and Planarians for Human Therapeutic Target Pathways

NI Mansor, TN Balqis, MN Lani, KL Lye… - International Journal of …, 2024 - mdpi.com
Despite significant improvements in the comprehension of neuro-regeneration, restoring
nerve injury in humans continues to pose a substantial therapeutic difficulty. In the …

Older spiny mice (Acomys cahirinus) have delayed and spatially heterogenous ear wound regeneration

JA Varholick, J Thermolice, G Godinez… - Biology …, 2024 - journals.biologists.com
ABSTRACT The African spiny mouse (Acomys cahirinus) is a unique mammalian model of
tissue regeneration, regenerating 4 mm ear-hole punches with cartilage, adipocytes, hair …

The Dynamic Landscapes of Circular RNAs in Axolotl, a Regenerative Medicine Model, with Implications for Early Phase of Limb Regeneration

T Demircan, BE Süzek - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
Circular RNAs (circRNAs) are of relevance to regenerative medicine and play crucial roles
in post-transcriptional and translational regulation of biological processes. circRNAs are a …

Post-amputation reactive oxygen species production is necessary for axolotls limb regeneration

B Carbonell-M, J Zapata Cardona… - Frontiers in Cell and …, 2022 - frontiersin.org
Introduction: Reactive oxygen species (ROS) represent molecules of great interest in the
field of regenerative biology since several animal models require their production to promote …

Mechanisms of regeneration: to what extent do they recapitulate development?

C Aztekin - Development, 2024 - journals.biologists.com
One of the enduring debates in regeneration biology is the degree to which regeneration
mirrors development. Recent technical advances, such as single-cell transcriptomics and …