Ynamides are among the most powerful building blocks in organic synthesis and have
become invaluable starting materials for the construction of multifunctional compounds and …

Umpolung approach through inversion of the polarity of conventional enolates, has opened
up an unprecedented opportunity in the cross‐coupling via alkylation. The enolonium …

An I2-catalyzed oxidative cross-coupling of α-amino ketones with a wide range of alcohols is
described. Using a combination of air and dimethyl sulfoxide (DMSO) as oxidants, the …

Abstract C–C and C–X bond forming reactions are essential tools in organic synthesis,
constantly revolutionizing human life. Among the key methods for constructing new chemical …

Gold (I)-catalyzed hetero-tetradehydro-Diels–Alder cycloaddition of enynamides and
cyanamides comprises an efficient route to diversely substituted 2, 6-diaminopyridines (28 …

An enantioselective intramolecular heterocyclization with in situ generated 3-
hydroxyisoindolinone-derived N-acyliminium ions has been successfully accomplished. In …

A formal haloalkynylation of allenamides has been described for the synthesis of highly
stereo-and regioselective skipped halo enynes. Exclusive γ-regioselectivity is achieved …

Chiral α-amino ketones are common structural motifs in natural products and
pharmaceuticals, as well as important synthons in organic synthesis. Thus, establishing …

AC–H bond cleavage-enabled aerobic ring-opening reaction of 2-aminobenzofuran-3 (2H)-
ones formed in situ by hemiacetals with a variety of amines is reported. This simple one-pot …

N, O-Acetals obtained from β-oxidation of ynamides underwent transacetalization with
benzotriazoles, leading to N, N-acetals. The Zn (OTf) 2 efficiently catalyzed the process, and …