A review on biological activities and chemical synthesis of hydrazide derivatives

R Narang, B Narasimhan… - Current medicinal …, 2012 - ingentaconnect.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antioxidant, hormone antagonist, analgesic, anti-inflammatory, antiplatelet …

A new insight into the synthesis and biological activities of pyrazole based derivatives

S Mor, M Khatri, R Punia, S Nagoria… - Mini-Reviews in …, 2022 - ingentaconnect.com
This review aims to collate literature work reported by researchers (from 1994 to 2021) to
provide an overview of the available methodologies for the synthesis and diverse …

[HTML][HTML] Analgesic, anti-inflammatory, antipyretic and toxicological evaluation of some newer 3-methyl pyrazolone derivatives

G Mariappan, BP Saha, L Sutharson, A Singh… - Saudi pharmaceutical …, 2011 - Elsevier
In this paper, we described the pharmacological and toxicological studies of three
pyrazolone derivatives namely PYZ1: 4-[4-N dimethylamino benzylidine]-3-methyl pyrazolin …

Design and Synthesis of Pyrazole‐3‐one Derivatives as Hypoglycaemic Agents

PA Datar, SR Jadhav - International Journal of Medicinal …, 2015 - Wiley Online Library
Pyrazole‐3‐one compounds were designed on the basis of docking studies of previously
reported antidiabetic pyrazole compounds. The amino acid residues found during docking …

4-Nitropyrazolin-5-ones as readily available fungicides of the novel structural type for crop protection: atom-efficient scalable synthesis and key structural features …

AS Budnikov, ER Lopat'eva, IB Krylov… - Journal of Agricultural …, 2022 - ACS Publications
The development of new types of fungicides for agriculture and medicine is highly desirable
due to the uprising fungal resistance against commonly used compounds. Herein, 4 …

Synthetic, spectroscopic, SC-XRD and nonlinear optical analysis of potent hydrazide derivatives: a comparative experimental and DFT/TD-DFT exploration

B Khan, M Khalid, MR Shah, MN Tahir, HM Asif… - Journal of Molecular …, 2020 - Elsevier
In this work, we reported the synthesis of hydrazide derivatives namely; N'-(4-(prop-2-
ynyloxy) benzylidene) isonicotinohydrazide (1) and 4-methyl-N'-(4 (prop-2-ynyloxy) …

Guanidine hydrochloride catalyzed efficient one-pot pseudo five-component synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) in water

F Noruzian, A Olyaei, R Hajinasiri… - Synthetic …, 2019 - Taylor & Francis
The present methodology describes an efficient, environmentally friendly and simple
protocol for the synthesis of some 4, 4′-(arylmethylene) bis (1 H-pyrazol-5-ol) derivatives …

N-Methylimidazolium perchlorate as a new ionic liquid for the synthesis of bis (pyrazol-5-ol) s under solvent-free conditions

NG Khaligh, SB Abd Hamid, SJJ Titinchi - Chinese Chemical Letters, 2016 - Elsevier
Abstract N-Methylimidazolium perchlorate ([MIm] ClO 4) was synthesized and some of its
physico-chemical properties, such as density, surface tension were investigated. A thermo …

Mild Nitration of Pyrazolin‐5‐ones by a Combination of Fe(NO3)3 and NaNO2: Discovery of a New Readily Available Class of Fungicides, 4‐Nitropyrazolin‐5‐ones

IB Krylov, AS Budnikov, ER Lopat'eva… - … A European Journal, 2019 - Wiley Online Library
Nitropyrazolin‐5‐ones have been synthesized by the nitration of pyrazolin‐5‐ones at room
temperature by employing the Fe (NO3) 3/NaNO2 system. The method demonstrated …

[HTML][HTML] The biological activity of new thieno [2, 3-c] pyrazole compounds as anti-oxidants against toxicity of 4-nonylphenol in Clarias gariepinus

AEDH Sayed, RM Zaki, AMK El-Dean, AY Abdulrazzaq - Toxicology reports, 2015 - Elsevier
Synthesis of bi functionally substituted thieno [2, 3-c] pyrazole compounds was carried out
by a new method. The substituted group at position five is namely (carbonitrile …