The interplay between extracellular matrix remodeling and cancer therapeutics
The extracellular matrix (ECM) is an abundant noncellular component of most solid tumors
known to support tumor progression and metastasis. The interplay between the ECM and …
known to support tumor progression and metastasis. The interplay between the ECM and …
Extracellular vesicles and matrix remodeling enzymes: the emerging roles in extracellular matrix remodeling, progression of diseases and tissue repair
Extracellular vesicles (EVs) are membrane enclosed micro-and nano-sized vesicles that are
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …
Roles of microvesicles in tumor progression and clinical applications
S Zhu, S Li, M Yi, N Li, K Wu - International Journal of …, 2021 - Taylor & Francis
Microvesicles are extracellular vesicles with diameter ranging from 100 to 1000 nm that are
secreted by tumor cells or other cells in the tumor microenvironment. A growing number of …
secreted by tumor cells or other cells in the tumor microenvironment. A growing number of …
Extracellular vesicles as regulators of the extracellular matrix
NJ Patel, A Ashraf, EJ Chung - Bioengineering, 2023 - mdpi.com
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the
extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids …
extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids …
The role of cancer-associated fibroblasts and extracellular vesicles in tumorigenesis
I Shoucair, F Weber Mello, J Jabalee, S Maleki… - International Journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) play a key role in the communication between cancer cells and
stromal components of the tumor microenvironment (TME). In this context, cancer cell …
stromal components of the tumor microenvironment (TME). In this context, cancer cell …
The activation of mesenchymal stem cells by glioblastoma microvesicles alters their exosomal secretion of miR-100-5p, miR-9-5p and let-7d-5p
Glioblastoma (GBM) is the most aggressive brain tumor, and despite initial response to
chemo-and radio-therapy, the persistence of glioblastoma stem cells (GSCs) unfortunately …
chemo-and radio-therapy, the persistence of glioblastoma stem cells (GSCs) unfortunately …
Role of CD147 (EMMPRIN/Basigin) in tissue remodeling
D Guindolet, EE Gabison - The Anatomical Record, 2020 - Wiley Online Library
ABSTRACT CD147, also known as extracellular matrix metalloproteinase inducer
(EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation …
(EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation …
Translational Aspects of Epithelioid Sarcoma: Current Consensus
TGP Grünewald, S Postel-Vinay, RT Nakayama… - Clinical Cancer …, 2024 - AACR
Epithelioid sarcoma (EpS) is an ultra-rare malignant soft-tissue cancer mostly affecting
adolescents and young adults. EpS often exhibits an unfavorable clinical course with fatal …
adolescents and young adults. EpS often exhibits an unfavorable clinical course with fatal …
Tumor-derived microvesicles for cancer therapy
S Yang, B Zheng, F Raza, S Zhang, W Yuan, J Su… - Biomaterials …, 2024 - pubs.rsc.org
Extracellular vesicles (EVs) are vesicles with lipid bilayer structures shed from the plasma
membrane of cells. Microvesicles (MVs) are a subset of EVs containing proteins, lipids …
membrane of cells. Microvesicles (MVs) are a subset of EVs containing proteins, lipids …
Structural insights on druggable hotspots in CD147: a bull's eye view
Abstract CD147/Basigin/EMMPRIN (Extracellular Matrix Metalloproteinase inducer) is a
single pass type1 transmembrane protein playing a central role in developmental process …
single pass type1 transmembrane protein playing a central role in developmental process …