Since its development about 40 years ago (1981–2021), Morris water maze has turned into
a very popular tool for assessing spatial learning and memory. Its many advantages have …

GABAergic inhibition shapes the connectivity, activity and plasticity of the brain. A series of
exciting new discoveries provides compelling evidence that disruptions in a number of key …

Inhibitory neurotransmission plays a key role in anxiety disorders, as evidenced by the
anxiolytic effect of the benzodiazepine class of γ-aminobutyric acid (GABA) receptor …

The genetics underlying autism spectrum disorder (ASD) is complex and heterogeneous,
and de novo variants are found in genes converging in functional biological processes …

Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

Postsynaptic organizational protein complexes play central roles both in orchestrating
synapse formation and in defining the functional properties of synaptic transmission that …

Neuroligins are postsynaptic cell adhesion molecules that are relevant to many
neurodevelopmental disorders. They are differentially enriched at the postsynapse and …

Schizophrenia is a chronic and severe mental disorder. It is currently treated with
antipsychotic drugs (APD). However, APD's work only in a limited number of patients and …

Current treatments of anxiety and depressive disorders are plagued by considerable side
effects and limited efficacies, underscoring the need for additional molecular targets that can …

Background: Schizophrenia is a serious mental illness that affects more than 21 million
people worldwide. Both genetics and the environment play a role in its etiology and …