Drug delivery research pursues many types of carriers including proteins and other
macromolecules, natural and synthetic polymeric structures, nanocarriers of diverse …

Nanoencapsulation is an approach to circumvent shortcomings such as reduced
bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic …

For four decades, liposomes composed of both naturally occurring and synthetic lipids have
been investigated as delivery vehicles for low molecular weight and macromolecular drugs …

Cholesterol (Chol) fortifies packing and reduces fluidity and permeability of the lipid bilayer
in vesicles (liposomes)-mediated drug delivery. However, under the physiological …

Liposomes improve the pharmacokinetics and safety of rapidly cleared drugs, but have not
yet improved the clinical efficacy compared to the non-encapsulated drug. This inability to …

We employed a recently introduced class of sterol-modified lipids (SML) to produce m-PEG-
DSPE containing liposome compositions with a range of cis-platinum content release rates …

Ideal drug carriers should be stable in biological environments but eventually release their
drug load once inside the targeted cells. These two aspects can be in contrast with each …

Liposomes represent a versatile drug formulation approach eg for improving the water-
solubility of poorly soluble drugs but also to achieve drug targeting and controlled release …

Lately, the usefulness of liposomal drug delivery systems has been debated. To better
understand the underlying pharmacokinetics of the targeted drug delivery by liposomes …

We synthesized and characterized two novel sterol-anchored polyethylene glycols (PEG) as
potential alternatives to conventional phosphatidylethanolamine-PEGs. Liposomes …