Zinc in wound healing modulation

PH Lin, M Sermersheim, H Li, PHU Lee, SM Steinberg… - Nutrients, 2017 - mdpi.com
Wound care is a major healthcare expenditure. Treatment of burns, surgical and trauma
wounds, diabetic lower limb ulcers and skin wounds is a major medical challenge with …

Critical role of zinc as either an antioxidant or a prooxidant in cellular systems

SR Lee - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Zinc is recognized as an essential trace metal required for human health; its deficiency is
strongly associated with neuronal and immune system defects. Although zinc is a redox …

Mitochondrial dysfunction: the hidden player in the pathogenesis of atherosclerosis?

G Ciccarelli, S Conte, G Cimmino, P Maiorano… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …

[HTML][HTML] Alcoholic liver disease: Utility of animal models

A Lamas-Paz, F Hao, LJ Nelson… - World journal of …, 2018 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) is a major cause of acute and chronic liver injury. Extensive
evidence has been accumulated on the pathological process of ALD during the past …

Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride‐induced liver fibrosis

JW Kang, JM Hong, SM Lee - Journal of pineal research, 2016 - Wiley Online Library
Liver fibrosis leads to liver cirrhosis and failure, and no effective treatment is currently
available. Growing evidence supports a link between mitochondrial dysfunction and liver …

Structure and hepatoprotective activity of Usp10/NF-κB/Nrf2 pathway-related Morchella esculenta polysaccharide

S Teng, Y Zhang, X Jin, Y Zhu, L Li, X Huang… - Carbohydrate …, 2023 - Elsevier
The water-soluble Morchella esculenta polysaccharide 2 (MEP2) was purified and isolated
from an aqueous extract of the Morchella esculenta fruiting bodies. MEP2, having a …

Mitochondrial dysfunction and liver disease: role, relevance, and potential for therapeutic modulation

P Middleton, N Vergis - Therapeutic Advances in …, 2021 - journals.sagepub.com
Mitochondria are key organelles involved in energy production as well as numerous
metabolic processes. There is a growing interest in the role of mitochondrial dysfunction in …

Mitochondrial dysfunction in atherosclerosis

W Peng, G Cai, Y Xia, J Chen, P Wu, Z Wang… - DNA and cell …, 2019 - liebertpub.com
Mitochondria are highly dynamic organelles beyond powerhouses of a cell. These
components also play important roles in cell homeostasis by regulating cell function and …

Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice

C Song, W Peng, S Yin, J Zhao, B Fu, J Zhang, T Mao… - Scientific reports, 2016 - nature.com
Increasing evidence shows that melatonin protected against age-related mitochondrial
oxidative damage. However, the protective effects of melatonin against ovarian aging has …

[HTML][HTML] HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway

BY Li, WQ Peng, Y Liu, L Guo, QQ Tang - Cell reports, 2023 - cell.com
Energy-dissipating adipocytes have the potential to improve metabolic health. Here, we
identify hypoxia-induced gene domain protein-1a (HIGD1A), a mitochondrial inner …