Pharmacological treatment of chemotherapy-induced neuropathic pain: PPARγ agonists as a promising tool

NLM Quintão, JR Santin, LC Stoeberl… - Frontiers in …, 2019 - frontiersin.org
Chemotherapy-induced neuropathic pain (CINP) is one of the most severe side effects of
anticancer agents, such as platinum-and taxanes-derived drugs (oxaliplatin, cisplatin …

[HTML][HTML] Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of osteosarcoma

C Zhang, JH Zheng, ZH Lin, HY Lv, ZM Ye… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
This work aimed to investigate tumor-infiltrating immune cells (TIICs) and immune-
associated genes in the tumor microenvironment of osteosarcoma. An algorithm known as …

[HTML][HTML] Peroxisome proliferator-activated receptors: Key regulators of tumor progression and growth

F Asgharzadeh, A Memarzia, V Alikhani, S Beigoli… - Translational …, 2024 - Elsevier
One of the main causes of death on the globe is cancer. Peroxisome-proliferator-activated
receptors (PPARs) are nuclear hormone receptors, including PPARα, PPARδ and PPARγ …

CPT2-mediated fatty acid oxidation inhibits tumorigenesis and enhances sorafenib sensitivity via the ROS/PPARγ/NF-κB pathway in clear cell renal cell carcinoma

K Zeng, Q Li, G Song, B Chen, M Luo, J Miao, B Liu - Cellular Signalling, 2023 - Elsevier
Kidney cancer is a common kind of tumor with approximately 400,000 new diagnoses each
year. Clear cell renal cell carcinoma (ccRCC) accounts for 70–80% of all renal cell …

A new prognostic risk model based on PPAR pathway‐related genes in kidney renal clear cell carcinoma

Y Xu, X Li, Y Han, Z Wang, C Han, N Ruan, J Li… - PPAR …, 2020 - Wiley Online Library
Objective. This study is aimed at using genes related to the peroxisome proliferator‐
activated receptor (PPAR) pathway to establish a prognostic risk model in kidney renal clear …

Identification of survival risk and immune‐related characteristics of kidney renal clear cell carcinoma

X Wu, Y Liang, X Chen, X Long, W Xu… - Journal of …, 2022 - Wiley Online Library
Background. Immunity exerts momentous functions in the progression and treatment of
kidney renal clear cell carcinoma (KIRC). A better understanding of the relationship between …

HOXC11 functions as a novel oncogene in human colon adenocarcinoma and kidney renal clear cell carcinoma

Y Cui, C Zhang, Y Wang, S Ma, W Cao, F Guan - Life sciences, 2020 - Elsevier
Aims Accumulating evidence has confirmed the involvement of the homeobox (HOX) gene
family in carcinogenesis. HOXC11, belongs to the homeobox-C (HOXC) gene cluster, has …

Integrated analysis of the expression characteristics, prognostic value, and immune characteristics of PPARG in breast cancer

J Wu, M Luo, Z Chen, L Li, X Huang - Frontiers in Genetics, 2021 - frontiersin.org
Background: Breast cancer (BRCA) is the most frequent malignancy. Identification of
potential biomarkers could help to better understand and combat the disease at early …

Differential expression profiles of the transcriptome and miRNA interactome in synovial fibroblasts of rheumatoid arthritis revealed by next generation sequencing

CC Tseng, LY Wu, WC Tsai, TT Ou, CC Wu, WY Sung… - Diagnostics, 2019 - mdpi.com
Using next-generation sequencing to decipher the molecular mechanisms underlying
aberrant rheumatoid arthritis synovial fibroblasts (RASF) activation, we performed …

Overexpression of sine oculis homeobox homolog 2 predicts poor survival and clinical parameters of patients with colon adenocarcinoma

Y Jiang, B Zhou, B Liang, F Zeng… - Annals of Clinical & …, 2020 - Assoc Clin Scientists
Objective. Sine oculis homeobox homolog 2 (Six2), a developmental transcription factor, is
known to be correlated with the development and prognosis of various cancers. In this study …