The Plasmodium liver stage represents a vulnerable therapeutic target to prevent disease
progression as the parasite resides in the liver before clinical representation caused by …

For Plasmodium falciparum, the most widespread and virulent malaria parasite that infects
humans, persistence depends on continuous asexual replication in red blood cells, while …

The use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand
the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein …

Malaria remains one of the most important public health problems, causing significant
morbidity and mortality. Malaria is a mosquito borne disease transmitted through an …

Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used
for the evaluation of anti-malarial compounds. Here, to screen for anti-malarial drugs …

Earlier genetic and inhibitor studies showed that epigenetic regulation of gene expression is
critical for malaria parasite survival in multiple life stages and a promising target for new …

Malaria remains one of the world's most life-threatening diseases and, thus, it is a major
public health concern all around the world. The disease can become devastating if not …

Malaria infection starts with the injection of Plasmodium sporozoites into the host's skin.
Sporozoites are motile and move in the skin to find and enter blood vessels to be carried to …

We recently adapted a CUT&RUN protocol for genome-wide profiling of chromatin
modifications in the human malaria parasite Plasmodium. Using the step-by-step protocol …

Like most pathogens, malaria parasites balance persistence in the current host with
transmission to the next. For Plasmodium falciparum, the most widespread and virulent …