The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities

Z Huang, AH Rose, PR Hoffmann - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Dietary selenium (] Se), mainly through its incorporation into selenoproteins, plays
an important role in inflammation and immunity. Adequate levels of Se are important for …

[HTML][HTML] Role of calpain system in meat tenderness: A review

ZF Bhat, JD Morton, SL Mason, AEDA Bekhit - Food Science and Human …, 2018 - Elsevier
Aging is a popular method used by meat industry for improving the sensory attributes of
meat. Despite the advent of many novel technologies, aging has not lost its charm and is still …

Membrane repair: mechanisms and pathophysiology

ST Cooper, PL McNeil - Physiological reviews, 2015 - journals.physiology.org
Eukaryotic cells have been confronted throughout their evolution with potentially lethal
plasma membrane injuries, including those caused by osmotic stress, by infection from …

Calpain research for drug discovery: challenges and potential

Y Ono, TC Saido, H Sorimachi - Nature Reviews Drug Discovery, 2016 - nature.com
Calpains are a family of proteases that were scientifically recognized earlier than
proteasomes and caspases, but remain enigmatic. However, they are known to participate in …

Biochemistry of postmortem muscle—Lessons on mechanisms of meat tenderization

EH Lonergan, W Zhang, SM Lonergan - Meat science, 2010 - Elsevier
It is certain that meat tenderness is a highly valued consumer trait and thus definition of the
multiple processes that influence meat tenderness will provide clues toward improving meat …

The calpain system

DE Goll, VF Thompson, H Li, WEI Wei… - Physiological …, 2003 - journals.physiology.org
Abstract Goll, Darrel E., Valery F. Thompson, Hongqi Li, Wei Wei, and Jinyang Cong. The
Calpain System. Physiol Rev 83: 731–801, 2003; 10.1152/physrev. 00029.2002.—The …

Calcium signaling: a tale for all seasons

E Carafoli - Proceedings of the National Academy of …, 2002 - National Acad Sciences
An experiment performed in London nearly 120 years ago, which by today's standards
would be considered unacceptably sloppy, marked the beginning of the calcium (Ca2+) …

[HTML][HTML] Calpains—An elaborate proteolytic system

Y Ono, H Sorimachi - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2012 - Elsevier
Calpain is an intracellular Ca2+-dependent cysteine protease (EC 3.4. 22.17; Clan CA,
family C02). Recent expansion of sequence data across the species definitively shows that …

The calpain system and cancer

SJ Storr, NO Carragher, MC Frame, T Parr… - Nature Reviews …, 2011 - nature.com
The calpains are a conserved family of cysteine proteinases that catalyse the controlled
proteolysis of many specific substrates. Calpain activity is implicated in several fundamental …

EF-hand calcium-binding proteins

A Lewit-Bentley, S Réty - Current opinion in structural biology, 2000 - Elsevier
The EF-hand motif is the most common calcium-binding motif found in proteins. Several high-
resolution structures containing different metal ions bound to EF-hand sites have given new …