Recent advances with liposomes as pharmaceutical carriers

VP Torchilin - Nature reviews Drug discovery, 2005 - nature.com
Liposomes—microscopic phospholipid bubbles with a bilayered membrane structure—have
received a lot of attention during the past 30 years as pharmaceutical carriers of great …

Multifunctional nanocarriers

VP Torchilin - Advanced drug delivery reviews, 2006 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …

Passive and active drug targeting: drug delivery to tumors as an example

VP Torchilin - Drug delivery, 2010 - Springer
The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …

Nanotechnology: intelligent design to treat complex disease

P Couvreur, C Vauthier - Pharmaceutical research, 2006 - Springer
The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …

Challenges in development of targeted liposomal therapeutics

RR Sawant, VP Torchilin - The AAPS journal, 2012 - Springer
Liposomes, phospholipid vesicles with a bilayered membrane structure, have been widely
used as pharmaceutical carriers for drugs and genes, in particular for treatment of cancer. To …

Targeted pharmaceutical nanocarriers for cancer therapy and imaging

VP Torchilin - The AAPS journal, 2007 - Springer
The use of various pharmaceutical nanocarriers has become one of the most important
areas of nanomedicine. Ideally, such carriers should be specifically delivered (targeted) to …

Multifunctional and stimuli-sensitive pharmaceutical nanocarriers

V Torchilin - European journal of pharmaceutics and …, 2009 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, and polymeric
nanoparticles, demonstrate a broad variety of useful properties, such as longevity in the …

pH‐Sensitive liposomes‐principle and application in cancer therapy

H Karanth, RSR Murthy - Journal of pharmacy and …, 2007 - Wiley Online Library
The purpose of this review is to provide an insight into the different aspects of pH‐sensitive
liposomes. The review consists of 6 parts: the first introduces different types of medications …

Liposomes as 'smart'pharmaceutical nanocarriers

RR Sawant, VP Torchilin - Soft Matter, 2010 - pubs.rsc.org
Since the discovery of liposomes, these phospholipid 'bubbles' have received enormous
attention to be recognized as 'smart'pharmaceutical nanocarriers. Recently, much effort has …

Therapeutic nanoparticles to combat cancer drug resistance

CMJ Hu, L Zhang - Current drug metabolism, 2009 - ingentaconnect.com
This review focuses on the application of drug-loaded nanoparticles (NPs), also called
therapeutic NPs, to combat cancer chemoresistance. Many cancer patients have …