Antibiotic renal dose adjustments are determined in patients with stable chronic kidney
disease and may not translate to patients in late-phase trials and practice. Ceftolozane …

Background Rapid initiation of antibiotic treatment is considered crucial in patients with
severe infections such as septic shock and bacterial meningitis, but may not be as important …

Background Effective antimicrobial treatment is key for survival in bloodstream infection
(BSI), but the impact of timing of treatment remains unclear. Our aim was to assess the …

Background: Blood cultures, the gold standard for diagnosing bloodstream infections (BSIs),
are insensitive and limited by prolonged time to results. The T2Bacteria Panel (T2 …

Background Patients with severe bacterial infections often experience delay in receiving
appropriate treatment. Consolidated evidence of the impact of delayed appropriate …

Objectives To evaluate the magnetic resonance-based T2Bacteria Panel assay for direct
detection of ESKAPEc (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

We discuss four studies in this issue of the Journal of Antimicrobial Chemotherapy that
describe experience with T2 magnetic resonance (T2MR) nanodiagnostics for Candida and …

Background Few published data are available on the morbidity and mortality of bloodstream
infections (BSIs) in Japan. We sought to investigate the epidemiology of BSIs, the …

Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of
otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute …

Background Bloodstream infections (BSI) are serious and life-threatening, associated with
high mortality and morbidity. In resource-limited settings, there is a paucity of data on …