[HTML][HTML] Gut neurotoxin p-cresol induces differential expression of GLUN2B and GLUN2A subunits of the NMDA receptor in the hippocampus and nucleus accumbens …
Mislocalization and abnormal expression of N-methyl-D-aspartate glutamate receptor
(NMDAR) subunits is observed in several brain disorders and pathological conditions …
(NMDAR) subunits is observed in several brain disorders and pathological conditions …
Gut neurotoxin p-cresol induces brain-derived neurotrophic factor secretion and increases the expression of neurofilament subunits in PC-12 cells
G Tevzadze, T Barbakadze, E Kvergelidze… - AIMS …, 2021 - pmc.ncbi.nlm.nih.gov
Increased p-cresol levels reportedly alter brain dopamine metabolism and exacerbate
neurological disorders in experimental animals. In contrast to toxic concentrations, low …
neurological disorders in experimental animals. In contrast to toxic concentrations, low …
Gut modulatory effects of flaxseed derived Maillard reaction products in Sprague-Dawley rats during sub-chronic toxicity
AR Zheng, CK Wei, ZJ Ni, K Thakur, JG Zhang… - Food and Chemical …, 2022 - Elsevier
Our study aimed to understand the effects of Maillard reaction products (MRPs) intake on
intestinal health, in vitro digestion, and fermentation metabolites in Sprague-Dawley (SD) …
intestinal health, in vitro digestion, and fermentation metabolites in Sprague-Dawley (SD) …
The link between covid-19-induced mental health complications and microbiota can exist
G Tevzadze, E Zhuravliova… - Journal of Mental …, 2021 - mentalhealthjournal.org
There have been recent reports of mental complications caused by COVID-19. Scientific
evidence, on the one hand, tells about the effect that COVID-19 has on mental health …
evidence, on the one hand, tells about the effect that COVID-19 has on mental health …
Effects of a Gut Microbiome Toxin, p-Cresol, on the Contents of the NMDA2B Receptor Subunit in the Nucl. Accumbens of Rats
The effects of p-cresol on the levels of subunit 2RB of NMDA receptors and also of AMPA
and GABAA receptors in the nucl. accumbens (NAc) of rats were studied. As was found, the …
and GABAA receptors in the nucl. accumbens (NAc) of rats were studied. As was found, the …
Bettering of Learning Activity through Elevated P-Cresol Levels in the Brain: Insights from Active Avoidance Testing in Wistar Rats
G Tevzadze, H Zhuravliova, Z Kikvidze, N Kiknadze… - bioRxiv, 2024 - biorxiv.org
It is established that p-cresol, a compound produced by bacterial colonies within the
gastrointestinal tract of mammals, plays a contributory role in the manifestation of various …
gastrointestinal tract of mammals, plays a contributory role in the manifestation of various …
[PDF][PDF] Besides the development of mental disorders, gut microbiome bacteria appear to play a major role in turning on cognitive activity: Outcomes of experiments …
G Tevzadze, L Shanshiashvili, D Mikeladze - 2024 - researchgate.net
The article discusses the findings of laboratory experiments conducted over the past seven
years, focusing on the investigation of the brain-gut axis. These experiments examine not …
years, focusing on the investigation of the brain-gut axis. These experiments examine not …
[PDF][PDF] Positive Effect of Elevated p-Cresol Level in the Brain through the Experiment on Rats: Insights from Active Avoidance Testing
G Tevzadze, Z Kikvidze - Contemporary Research and Perspectives in … - researchgate.net
The present study highlights the positive effect of elevated p-cresol levels in the brain
through the experiment on rats. It is established that p-cresol, a compound produced by …
through the experiment on rats. It is established that p-cresol, a compound produced by …