Large-scale neurophysiology and single-cell profiling in human neuroscience
Advances in large-scale single-unit human neurophysiology, single-cell RNA sequencing,
spatial transcriptomics and long-term ex vivo tissue culture of surgically resected human …
spatial transcriptomics and long-term ex vivo tissue culture of surgically resected human …
Dynamic amplitude modulation of microstimulation evokes biomimetic onset and offset transients and reduces depression of evoked calcium responses in sensory …
Background Intracortical microstimulation (ICMS) is an emerging approach to restore
sensation to people with neurological injury or disease. Biomimetic microstimulation, or …
sensation to people with neurological injury or disease. Biomimetic microstimulation, or …
Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health
Intracortical microelectrodes have become a useful tool in neuroprosthetic applications in
the clinic and to understand neurological disorders in basic neurosciences. Many of these …
the clinic and to understand neurological disorders in basic neurosciences. Many of these …
Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome
F Capitano, M Kuchenbuch, J Lavigne… - Proceedings of the …, 2024 - National Acad Sciences
Epilepsies have numerous specific mechanisms. The understanding of neural dynamics
leading to seizures is important for disclosing pathological mechanisms and developing …
leading to seizures is important for disclosing pathological mechanisms and developing …
Optimal decoding of neural dynamics occurs at mesoscale spatial and temporal resolutions
Introduction Understanding the neural code has been one of the central aims of
neuroscience research for decades. Spikes are commonly referred to as the units of …
neuroscience research for decades. Spikes are commonly referred to as the units of …
Neuronal functional connectivity is impaired in a layer dependent manner near chronically implanted intracortical microelectrodes in C57BL6 wildtype mice
K Chen, A Forrest, G Gonzalez Burgos… - Journal of Neural …, 2024 - iopscience.iop.org
Objective: This study aims to reveal longitudinal changes in functional network connectivity
within and across different brain structures near chronically implanted microelectrodes …
within and across different brain structures near chronically implanted microelectrodes …
Hippocampal and Medial Prefrontal Cortex Fractal Spiking Patterns Encode Episodes and Rules
A Srinivasan, A Srinivasan, MR Goodman… - Chaos, Solitons & …, 2023 - Elsevier
A central question in neuroscience is how the brain represents and processes information to
guide behavior. The principles that organize brain computations are not fully known, and …
guide behavior. The principles that organize brain computations are not fully known, and …
[HTML][HTML] Deep learning models for atypical serotonergic cells recognition
D Corradetti, A Bernardi, R Corradetti - Journal of Neuroscience Methods, 2024 - Elsevier
Background: The serotonergic system modulates brain processes via functionally distinct
subpopulations of neurons with heterogeneous properties, including their …
subpopulations of neurons with heterogeneous properties, including their …
Neuronal functional connectivity is impaired in a layer dependent manner near the chronically implanted microelectrodes
Objective: This study aims to reveal longitudinal changes in functional network connectivity
within and across different brain structures near the chronically implanted microelectrode …
within and across different brain structures near the chronically implanted microelectrode …