Members of the protein superfamily of small guanosine triphosphatases, also known as
small GTPases, small G-proteins, or the Ras superfamily, are involved in nearly every aspect …

Highly regulated cell migration events are crucial during animal tissue formation and the
trafficking of cells to sites of infection and injury. Misregulation of cell movement underlies …

Development of the C. elegans gonad has long been studied as a model of organogenesis
driven by collective cell migration. A somatic cell named the distal tip cell (DTC) is thought to …

The proliferation/differentiation balance of stem and progenitor cell populations must
respond to the physiological needs of the organism [1, 2]. Mechanisms underlying this …

NFκB is one of the central regulators of cell survival, immunity, inflammation, carcinogenesis
and organogenesis. The activation of NFκB is strictly regulated by several posttranslational …

The advantages from exogenously applied RNAi biopesticides have yet to be realized in
through commercialization due to inconsistent activity of the dsRNA trigger, and the activity …

Cactin was originally identified as an interactor of the Drosophila IκB factor Cactus and
shown to play a role in controlling embryonic polarity and regulating the NF-κB signaling …

The proper accumulation and maintenance of stem cells is critical for organ development
and homeostasis. The Notch signaling pathway maintains stem cells in diverse organisms …

Cell migration and morphogenesis are key events in tissue development and
organogenesis. In Caenorhabditis elegans, the migratory path of the distal tip cells …

Migrating cells and growth cones extend lamellipodial and filopodial protrusions that are
required for outgrowth and guidance. The mechanisms of cytoskeletal regulation that …