The inability to make broad, minimally biased measurements of a cell's proteome stands as
a major bottleneck for understanding how gene expression translates into cellular …

NF-κB is generally recognized as an important regulator of ageing, through its roles in
cellular senescence and inflammatory pathways. Activated in virtually all cell-cell …

Profiling protein expression at single‐cell resolution is essential for fundamental biological
research (such as cell differentiation and tumor microenvironmental examination) and …

Chimeric antigen receptor (CAR)-T cell therapies against cancer continue to make inroads
in the clinic. However, progress is still hindered by subpar efficacy against many tumors …

For a long time, post-mortem analysis of human brain pathologies has been purely
descriptive, limiting insight into the pathological mechanisms. However, starting in the early …

The spatial organization of transmembrane proteins helps to regulate intracellular signal
transmission which contributes to biological processes and diseases. Bottom-up proximity …