Global epidemiology and outcomes of acute kidney injury

EAJ Hoste, JA Kellum, NM Selby, A Zarbock… - Nature Reviews …, 2018 - nature.com
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

A Levin, M Tonelli, J Bonventre, J Coresh, JA Donner… - The Lancet, 2017 - thelancet.com
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Neonatal acute kidney injury

DT Selewski, JR Charlton, JG Jetton, R Guillet… - …, 2015 - publications.aap.org
In recent years, there have been significant advancements in our understanding of acute
kidney injury (AKI) and its impact on outcomes across medicine. Research based on single …

The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction

RL Chevalier - American Journal of Physiology-Renal …, 2016 - journals.physiology.org
There is an alarming global increase in the incidence of end-stage kidney disease, for which
early biomarkers and effective treatment options are lacking. Largely based on the histology …

[HTML][HTML] AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms

L He, Q Wei, J Liu, M Yi, Y Liu, H Liu, L Sun, Y Peng… - Kidney international, 2017 - Elsevier
Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected. Although
AKI-to-CKD transition has been intensively studied, the information of AKI on CKD is very …

Acute kidney injury: an increasing global concern

NH Lameire, A Bagga, D Cruz, J De Maeseneer… - The Lancet, 2013 - thelancet.com
Despite an increasing incidence of acute kidney injury in both high-income and low-income
countries and growing insight into the causes and mechanisms of disease, few preventive …

[PDF][PDF] Acute kidney injury—epidemiology, outcomes and economics

O Rewa, SM Bagshaw - Nature reviews nephrology, 2014 - nature.com
Acute kidney injury (AKI) is a widespread problem of epidemic status. Compelling evidence
indicates that the incidence of AKI is rapidly increasing, particularly among hospitalized …

International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology

RL Mehta, J Cerdá, EA Burdmann, M Tonelli… - The Lancet, 2015 - thelancet.com
Executive summary Acute kidney injury (AKI) is a major contributor to poor patient outcomes.
AKI occurs in about 13· 3 million people per year, 85% of whom live in the developing world …

AKI in hospitalized children: comparing the pRIFLE, AKIN, and KDIGO definitions

SM Sutherland, JJ Byrnes, M Kothari… - Clinical Journal of the …, 2015 - journals.lww.com
Results AKI incidences across the cohort according to pRIFLE, AKIN, and KDIGO were
51.1%, 37.3%, and 40.3%. Mortality was higher among patients with AKI across all …

Acute kidney injury recovery pattern and subsequent risk of CKD: an analysis of veterans health administration data

M Heung, DE Steffick, K Zivin, BW Gillespie… - American Journal of …, 2016 - Elsevier
Background Studies suggest an association between acute kidney injury (AKI) and long-
term risk for chronic kidney disease (CKD), even following apparent renal recovery. Whether …