Conformational stability and denaturation processes of proteins investigated by electrophoresis under extreme conditions

P Masson, S Lushchekina - Molecules, 2022 - mdpi.com
The functional structure of proteins results from marginally stable folded conformations.
Reversible unfolding, irreversible denaturation, and deterioration can be caused by …

Recombinant Proteins for Assembling as Nano-and Micro-Scale Materials for Drug Delivery: A Host Comparative Overview

JL Corchero, MTP Favaro, M Márquez-Martínez… - Pharmaceutics, 2023 - mdpi.com
By following simple protein engineering steps, recombinant proteins with promising
applications in the field of drug delivery can be assembled in the form of functional materials …

A review of fifteen years developing computational tools to study protein aggregation

C Pintado-Grima, O Bárcenas, A Bartolomé-Nafría… - Biophysica, 2023 - mdpi.com
The presence of insoluble protein deposits in tissues and organs is a hallmark of many
human pathologies. In addition, the formation of protein aggregates is considered one of the …

[HTML][HTML] High-precision targeting and destruction of cancer-associated PDGFR-β+ stromal fibroblasts through self-assembling, protein-only nanoparticles

E Voltà-Durán, L Alba-Castellón, N Serna, I Casanova… - Acta biomaterialia, 2023 - Elsevier
The need for more effective and precision medicines for cancer has pushed the exploration
of new materials appropriate for drug delivery and imaging, and alternative receptors for …

Click, Compute, Create: A Review of Web‐based Tools for Enzyme Engineering

A Tripp, M Braun, F Wieser, G Oberdorfer… - …, 2024 - Wiley Online Library
Enzyme engineering, though pivotal across various biotechnological domains, is often
plagued by its time‐consuming and labor‐intensive nature. This review aims to offer an …