Mitochondrial membrane lipids in the regulation of bioenergetic flux

ST Decker, K Funai - Cell metabolism, 2024 - cell.com
Oxidative phosphorylation (OXPHOS) occurs through and across the inner mitochondrial
membrane (IMM). Mitochondrial membranes contain a distinct lipid composition, aided by …

Cardiometabolic effects of sacubitril/valsartan in a rat model of heart failure with preserved ejection fraction

S Moraña-Fernández, X Vázquez-Abuín… - Biochemical …, 2024 - Elsevier
The promising results obtained in the PARADIGM-HF trial prompted the approval of
sacubitril/valsartan (SAC/VAL) as a first-in-class treatment for heart failure with reduced …

[HTML][HTML] Specific Substrate Activity of Lotus Root Polyphenol Oxidase: Insights from Gaussian-Accelerated Molecular Dynamics and Markov State Models

M Liu, S Zheng, Y Tang, W Han, W Li, T Li - International Journal of …, 2024 - mdpi.com
Polyphenol oxidase (PPO) plays a key role in the enzymatic browning process, and this
study employed Gaussian-accelerated molecular dynamics (GaMD) simulations to …

Poration of mitochondrial membranes by amyloidogenic peptides and other biological toxins

N Vassallo - Journal of Neurochemistry - Wiley Online Library
Mitochondria are essential organelles known to serve broad functions, including in cellular
metabolism, calcium buffering, signaling pathways and the regulation of apoptotic cell death …