Click chemistry strategies for the accelerated synthesis of functional macromolecules
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …
materials with precise control over architecture and functionality. In this review, we provide a …
Developing bioorthogonal probes to span a spectrum of reactivities
SS Nguyen, JA Prescher - Nature Reviews Chemistry, 2020 - nature.com
Bioorthogonal chemistries enable researchers to interrogate biomolecules in living systems.
These reactions are highly selective and biocompatible, and can be performed in many …
These reactions are highly selective and biocompatible, and can be performed in many …
Insights on chemical crosslinking strategies for proteins
Crosslinking of proteins has gained immense significance in the fabrication of biomaterials
for various health care applications. Various novel chemical-based strategies are being …
for various health care applications. Various novel chemical-based strategies are being …
Polyphenols as antioxidant/pro-oxidant compounds and donors of reducing species: relationship with human antioxidant metabolism
CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Processes, 2023 - mdpi.com
In this review, we have focused mainly on the study of their antioxidant and pro-oxidant
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …
Catalytic activation of bioorthogonal chemistry with light (CABL) enables rapid, spatiotemporally controlled labeling and no-wash, subcellular 3D-patterning in live …
Described is the spatiotemporally controlled labeling and patterning of biomolecules in live
cells through the catalytic activation of bioorthogonal chemistry with light, referred to as …
cells through the catalytic activation of bioorthogonal chemistry with light, referred to as …
Juglone in oxidative stress and cell signaling
T Ahmad, YJ Suzuki - Antioxidants, 2019 - mdpi.com
Juglone (5-hydroxyl-1, 4-naphthoquinone) is a phenolic compound found in walnuts.
Because of the antioxidant capacities of phenolic compounds, juglone may serve to combat …
Because of the antioxidant capacities of phenolic compounds, juglone may serve to combat …
Recent developments in the cleavage, functionalization, and conjugation of proteins and peptides at tyrosine residues
Peptide and protein selective modification at tyrosine residues has become an exploding
field of research as tyrosine constitutes a robust alternative to lysine and cysteine-targeted …
field of research as tyrosine constitutes a robust alternative to lysine and cysteine-targeted …
Enabling In Vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Silicon-Rhodamine Fluorophores as Cytocompatible Far-Red …
Chromophores that absorb in the tissue-penetrant far-red/near-infrared window have long
served as photocatalysts to generate singlet oxygen for photodynamic therapy. However, the …
served as photocatalysts to generate singlet oxygen for photodynamic therapy. However, the …
Oxidation-induced “one-pot” click chemistry
Click chemistry has been established rapidly as one of the most valuable methods for the
chemical transformation of complex molecules. Due to the rapid rates, clean conversions to …
chemical transformation of complex molecules. Due to the rapid rates, clean conversions to …
Bioconjugation in materials science
C Bednarek, U Schepers, F Thomas… - Advanced Functional …, 2024 - Wiley Online Library
With the advent of bioconjugation chemistry in the last two decades, highlighted by the
Nobel Prize 2022, the quest for possible novel applications has been greatly intensified …
Nobel Prize 2022, the quest for possible novel applications has been greatly intensified …