Single-cell RNA sequencing (scRNA-Seq) is a recent technology that allows for the
measurement of the expression of all genes in each individual cell contained in a sample …

Quantifying cell-type proportions and their corresponding gene expression profiles in tissue
samples would enhance understanding of the contributions of individual cell types to the …

Tissue immune cells have long been recognized as important regulators for the
maintenance of balance in the body system. Quantification of the abundance of different …

Computational deconvolution is a time and cost-efficient approach to obtain cell type-
specific information from bulk gene expression of heterogeneous tissues like blood …

Toxicogenomics databases are useful for understanding biological responses in individuals
because they include a diverse spectrum of biological responses. Although these databases …

The importance of cell type-specific gene expression in disease-relevant tissues is
increasingly recognized in genetic studies of complex diseases. However, most gene …

Background: The utilization of genetic data to investigate biological problems has recently
become a vital approach. However, it is undeniable that the heterogeneity of original …

Cell-type deconvolution methods aim to infer cell-type composition and the cell abundances
from bulk transcriptomic data. The proliferation of currently developed methods (> 50) …

Motivation Molecular signatures are critical for inferring the proportions of cell types from
bulk transcriptomics data. However, the identification of these signatures is based on a …

The utilization of genetic data to investigate toxicological problems has become an
imperative approach. Toxicogenomics (TGx), as a specialty branch created by the merger of …