Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …

Life under extreme energy limitation: a synthesis of laboratory-and field-based investigations

MA Lever, KL Rogers, KG Lloyd… - FEMS microbiology …, 2015 - academic.oup.com
The ability of microorganisms to withstand long periods with extremely low energy input has
gained increasing scientific attention in recent years. Starvation experiments in the …

Bioprospecting for hyper-lipid producing microalgal strains for sustainable biofuel production

T Mutanda, D Ramesh, S Karthikeyan, S Kumari… - Bioresource …, 2011 - Elsevier
Global petroleum reserves are shrinking at a fast pace, increasing the demand for alternate
fuels. Microalgae have the ability to grow rapidly, and synthesize and accumulate large …

Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery

GT Vladisavljević, N Khalid, MA Neves… - Advanced drug delivery …, 2013 - Elsevier
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …

Microfluidic sample preparation for single cell analysis

S Hosic, SK Murthy, AN Koppes - Analytical chemistry, 2016 - ACS Publications
Single cell analysis is the measurement of transcription, translation, regulatory, and
signaling events within individual cells at the molecular level. The goal is to analyze and …

Microfluidic particle sorter employing flow splitting and recombining

M Yamada, M Seki - Analytical chemistry, 2006 - ACS Publications
This paper describes an improved microfluidic device that enables hydrodynamic particle
concentration and size-dependent separation to be carried out in a continuous manner. In …

Microfluidic sorting system based on optical waveguide integration and diode laser bar trapping

RW Applegate Jr, J Squier, T Vestad, J Oakey… - Lab on a Chip, 2006 - pubs.rsc.org
Effective methods for manipulating, isolating and sorting cells and particles are essential for
the development of microfluidic-based life science research and diagnostic platforms. We …

An on-chip imaging droplet-sorting system: a real-time shape recognition method to screen target cells in droplets with single cell resolution

M Girault, H Kim, H Arakawa, K Matsuura, M Odaka… - Scientific reports, 2017 - nature.com
A microfluidic on-chip imaging cell sorter has several advantages over conventional cell
sorting methods, especially to identify cells with complex morphologies such as clusters …

Translating microfluidics: Cell separation technologies and their barriers to commercialization

CW Shields IV, KA Ohiri, LM Szott… - Cytometry Part B …, 2017 - Wiley Online Library
Advances in microfluidic cell sorting have revolutionized the ways in which cell‐containing
fluids are processed, now providing performances comparable to, or exceeding, traditional …

Acoustofluidic fluorescence activated cell sorter

AA Nawaz, Y Chen, N Nama, RH Nissly, L Ren… - Analytical …, 2015 - ACS Publications
Selective isolation of cell subpopulations with defined biological characteristics is crucial for
many biological studies and clinical applications. In this work, we present the development …