Exosomes: A potential tool for immunotherapy of ovarian cancer

X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …

Management strategies for recurrent endometrial cancer

EV Connor, PG Rose - Expert Review of Anticancer Therapy, 2018 - Taylor & Francis
Introduction: Endometrial cancer is the most common gynecologic malignancy in the
developed world, and its incidence is increasing. Mortality from this cancer has not improved …

Efficacy and safety of nivolumab in Japanese patients with uterine cervical cancer, uterine corpus cancer, or soft tissue sarcoma: Multicenter, open‐label phase 2 trial

K Tamura, K Hasegawa, N Katsumata… - Cancer …, 2019 - Wiley Online Library
Nivolumab is a human monoclonal antibody against the immune checkpoint receptor
programmed death‐1, inhibiting binding to programmed death‐ligand 1 or 2 (PD‐L1 or PD …

New therapies for advanced, recurrent, and metastatic endometrial cancers

V Makker, AK Green, RM Wenham, D Mutch… - … oncology research and …, 2017 - Springer
Endometrial cancer is the most common gynecologic malignancy in the United States,
accounting for 6% of cancers in women. In 2017, an estimated 61,380 women were …

Metformin suppresses cancer cell growth in endometrial carcinoma by inhibiting PD-L1

J Xue, L Li, N Li, F Li, X Qin, T Li, M Liu - European journal of pharmacology, 2019 - Elsevier
Endometrial cancer is the most common cancer of the female reproductive system in the
developed countries. Metformin is a widely used medication that has been prescribed to …

Expression of PD-1 and PD-L1 in endometrial cancer: molecular and clinical significance

MN Mamat@ Yusof, KT Chew, NC Kampan… - International Journal of …, 2023 - mdpi.com
The landscape of diagnosing and treating endometrial cancer is undergoing a profound
transformation due to the integration of molecular analysis and innovative therapeutic …

New insights for gynecological cancer therapies: from molecular mechanisms and clinical evidence to future directions

C Zhang, Y Sheng, X Sun, Y Wang - Cancer and Metastasis Reviews, 2023 - Springer
Advanced and recurrent gynecological cancers lack effective treatment and have poor
prognosis. Besides, there is urgent need for conservative treatment for fertility protection of …

PD-L1 expression in endometrial cancer and its association with clinicopathological features: a systematic review and meta-analysis

MN Mamat@ Yusof, KT Chew, N Kampan… - Cancers, 2022 - mdpi.com
Simple Summary In women, endometrial cancer is a crucial cancer cause-death, which is
still not fully explored in its pathogenesis and immune system. Early detection is essential for …

[HTML][HTML] Recent advances in endometrial cancer: a review of key clinical trials from 2015 to 2019

LM Charo, SC Plaxe - F1000Research, 2019 - ncbi.nlm.nih.gov
In the past few years, we have seen several important advances in understanding of and
therapy for endometrial cancer. This review highlights key recent abstracts and publications …

Posttranscriptional control of PD-L1 expression by 17β-estradiol via PI3K/Akt signaling pathway in ERα-positive cancer cell lines

L Yang, F Huang, J Mei, X Wang, Q Zhang… - International Journal of …, 2017 - ijgc.bmj.com
Objective Estrogen is a well-known oncogenic driver in endometrial (ECs) and breast
cancers (BCs). Programmed cell death protein 1 (PD-1) and its ligands PD-1 Ligand 1 (PD …