[HTML][HTML] Neuromodulation of hippocampal long-term synaptic plasticity

J Palacios-Filardo, JR Mellor - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Acetylcholine, noradrenaline, dopamine and serotonin all facilitate long-term
synaptic plasticity.•Neuromodulators facilitate long-term synaptic plasticity by common and …

Central nervous system effects of 5-HT7 receptors: a potential target for neurodegenerative diseases

A Quintero-Villegas, SI Valdés-Ferrer - Molecular Medicine, 2022 - Springer
HT7 receptors (5-HT7R) are the most recently identified among the family of serotonin
receptors. Their role in health and disease, particularly as mediators of, and druggable …

Dysfunction of cortical dendritic integration in neuropathic pain reversed by serotoninergic neuromodulation

M Santello, T Nevian - Neuron, 2015 - cell.com
Neuropathic pain is caused by long-term modifications of neuronal function in the peripheral
nervous system, the spinal cord, and supraspinal areas. Although functional changes in the …

Genetic and biochemical changes of the serotonergic system in migraine pathobiology

CF Gasparini, RA Smith, LR Griffiths - The journal of headache and pain, 2017 - Springer
Migraine is a brain disorder characterized by a piercing headache which affects one side of
the head, located mainly at the temples and in the area around the eye. Migraine imparts …

Role of the serotonin receptor 7 in brain plasticity: From development to disease

M Crispino, F Volpicelli, C Perrone-Capano - International journal of …, 2020 - mdpi.com
Our knowledge on the plastic functions of the serotonin (5-HT) receptor subtype 7 (5-HT7R)
in the brain physiology and pathology have advanced considerably in recent years. A wealth …

Therapeutic potential and limitation of serotonin type 7 receptor modulation

K Fukuyama, E Motomura, M Okada - International Journal of Molecular …, 2023 - mdpi.com
Although a number of mood-stabilising atypical antipsychotics and antidepressants
modulate serotonin type 7 receptor (5-HT7), the detailed contributions of 5-HT7 function to …

Cellular mechanisms of the 5-HT7 receptor-mediated signaling

D Guseva, A Wirth, E Ponimaskin - Frontiers in behavioral …, 2014 - frontiersin.org
Serotonin (5-hydroxytryptamine or 5-HT) is an important neurotransmitter regulating a wide
range of physiological and pathological functions via activation of heterogeneously …

Current limitations and candidate potential of 5-HT7 receptor antagonism in psychiatric pharmacotherapy

R Okubo, T Hasegawa, K Fukuyama… - Frontiers in …, 2021 - frontiersin.org
Several mood-stabilizing atypical antipsychotics and antidepressants weakly block
serotonin (5-HT) receptor type-7 (5-HT7R); however, the contributions of 5-HT7R …

[HTML][HTML] 5-HT7 receptors in Alzheimer's disease

M Solas, D Van Dam, J Janssens, U Ocariz… - Neurochemistry …, 2021 - Elsevier
Even though the involvement of serotonin (5-hydroxytryptamine; 5-HT) and its receptors in
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …

The 5-Hydroxytryptamine signaling map: an overview of serotonin-serotonin receptor mediated signaling network

A Sahu, L Gopalakrishnan, N Gaur… - Journal of Cell …, 2018 - Springer
The monoamine neurotransmitter, 5-Hydroxytryptamine or serotonin, is derived from
tryptophan and synthesized both centrally and systemically. Fourteen structurally and …