State of the art: the immunomodulatory role of MSCs for osteoarthritis

DG Kwon, MK Kim, YS Jeon, YC Nam, JS Park… - International journal of …, 2022 - mdpi.com
Osteoarthritis (OA) has generally been introduced as a degenerative disease; however, it
has recently been understood as a low-grade chronic inflammatory process that could …

Advances in microRNA from adipose-derived mesenchymal stem cell-derived exosome: focusing on wound healing

J Ma, L Yong, P Lei, H Li, Y Fang, L Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Skin wounds are a common condition causing economic burden and they represent an
urgent clinical need, especially chronic wounds. Numerous studies have been conducted on …

MSC-EVs alleviate osteoarthritis by regulating microenvironmental cells in the articular cavity and maintaining cartilage matrix homeostasis

B You, C Zhou, Y Yang - Ageing research reviews, 2023 - Elsevier
Osteoarthritis (OA), a common cause of chronic articular cartilage degeneration, is the main
cause of disability in older adults and severely affects quality of life. Multiple factors are …

Small extracellular vesicles' miRNAs: biomarkers and therapeutics for neurodegenerative diseases

WQ Lim, KH Michelle Luk, KY Lee, N Nurul, SJ Loh… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative diseases are critical in the healthcare system as patients suffer from
progressive diseases despite currently available drug management. Indeed, the growing …

3D culture and interferon-γ Priming modulates characteristics of mesenchymal stromal/stem cells by modifying the expression of both intracellular and exosomal …

M Bulati, A Gallo, G Zito, R Busà, G Iannolo, N Cuscino… - Biology, 2023 - mdpi.com
Simple Summary With the aim of improving the therapeutic potential of mesenchymal
stromal/stem cells (MSCs), we analyzed miRNA expression to investigate the effects of …

A state-of-the-art review on the MicroRNAs roles in hematopoietic stem cell aging and longevity

GGR Ortiz, Y Mohammadi, A Nazari… - Cell Communication and …, 2023 - Springer
Aging is a biological process determined through time-related cellular and functional
impairments, leading to a decreased standard of living for the organism. Recently, there has …

Exosomes based advancements for application in medical aesthetics

B Zhang, J Gong, L He, A Khan, T Xiong… - … in Bioengineering and …, 2022 - frontiersin.org
Beauty is an eternal pursuit of all people. Wound repair, anti-aging, inhibiting
hyperpigmentation and hair loss are the main demands for medical aesthetics. At present …

Extracellular vesicles in facial aesthetics: a review

LT Kee, CY Ng, ME Al-Masawa, JB Foo… - International Journal of …, 2022 - mdpi.com
Facial aesthetics involve the application of non-invasive or minimally invasive techniques to
improve facial appearance. Currently, extracellular vesicles (EVs) are attracting much …

[HTML][HTML] Injectable hydrogels for sustained delivery of extracellular vesicles in cartilage regeneration

SM van de Looij, OG de Jong, T Vermonden… - Journal of Controlled …, 2023 - Elsevier
Extracellular vesicles (EVs) are a population of small vesicles secreted by essentially all cell
types, containing a wide variety of biological macromolecules. Due to their intrinsic …

Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis

D Luo, H Zhu, S Li, Z Wang, J Xiao - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Osteoarthritis (OA), as a degenerative disease, leads to high socioeconomic burdens and
disability rates. The knee joint is typically the most affected and is characterized by …