Introduction Indolizines are structural isomers with indoles. Although several indole-based
commercial drugs are available in the market, none of the indolizine-based drugs are …

Human tuberculosis (TB) is primarily caused by Mycobacterium tuberculosis (Mtb) that
inhabits inside and amidst immune cells of the host with adapted physiology to regulate …

Mycobacterial pathogens present a significant challenge to disease control efforts globally
due to their inherent resistance to multiple antibiotics. The rise of drug-resistant strains of …

A series of novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues (4a-r)
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …

Abstract A series of 1, 2, 3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …

The alarming increase in multi-and extensively drug-resistant (MDR and XDR) strains of
Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for …

An efficient I2-promoted one-pot one-step three-component reaction for the synthesis of
sulfhydryl indolizines from methyl ketones, 2-pyridylacetate derivatives, and sulfonyl …

Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …

In the present investigation, the parent compound 4-amino-5-(4-fluoro-3-phenoxyphenyl)-4
H-1, 2, 4-triazole-3-thiol (1) and its Schiff bases 2, 3, and 4 were subjected to whole-cell anti …

A series of ethyl 1-(substituted benzoyl)-5-methylpyrrolo [1, 2-a] quinoline-3-carboxylates 4a–
f and dimethyl 1-(substituted benzoyl)-5-methylpyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates …