Therapeutic potential of rutin in male infertility: a mini review

DE Rotimi, TC Elebiyo, OA Ojo - Journal of Integrative Medicine, 2023 - Elsevier
Male infertility has become a problem worldwide, and recent research has emphasized the
development of more effective therapy options. Among natural compounds, rutin has been …

Oxidative stress-induced hormonal disruption in male reproduction

DE Rotimi, MA Acho, BM Falana, TD Olaolu… - Reproductive …, 2024 - Springer
Research into the impacts of oxidative stress (OS), and hormonal balance on reproductive
potential has increased over the last 40 years possibly due to rising male infertility …

Smoking induces a decline in semen quality and the activation of stress response pathways in sperm

MC Henriques, J Santiago, A Patrício, MT Herdeiro… - Antioxidants, 2023 - mdpi.com
Male infertility is a prevalent concern affecting couples worldwide. While genetic factors,
hormonal imbalances, and reproductive system defects play significant roles, emerging …

Pharmacological action of quercetin against testicular dysfunction: A mini review

DE Rotimi, TD Olaolu, OS Adeyemi - Journal of Integrative Medicine, 2022 - Elsevier
The testis is an immune-privileged organ susceptible to oxidative stress and inflammation,
two major factors implicated in male infertility. A reduction in the concentration and activities …

[HTML][HTML] Implications of lifestyle factors on male reproductive health

DE Rotimi, SK Singh - JBRA Assisted Reproduction, 2024 - ncbi.nlm.nih.gov
In recent decades, there has been a substantial decline in sperm quality in humans, with
lifestyle factors playing a major role in this trend. There are several lifestyle factors which are …

[HTML][HTML] Impact of Watermelon (Citrallus lanatus) on Male Fertility

DE Rotimi, RM Asaleye - JBRA assisted reproduction, 2023 - ncbi.nlm.nih.gov
Plants have been used in various regions of the world to treat various medical conditions
including male infertility. The review aims to evaluate the pharmacological effects of …

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

CO Nwonuma, VC Nwatu, G Mostafa-Hedeab… - … medicine and therapies, 2022 - Springer
Background Data available support that ninety percent of male infertility cases are due to
low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility …

Dietary Polyphenols in Male Infertility: Mechanistic Approach

DE Rotimi, AE Shalom, OP Rotimi… - … and Business for …, 2024 - ieeexplore.ieee.org
Male infertility affects a sizable portion of trying-to-conceive couples, and it is a rising global
concern. Oxidative stress has been identified as a fundamental mechanism that disrupts …

Modulatory Effects of Ethanol with Nicotiana Tabacum and Cannabis Sativa on Markers of Brain Function and Haematological Parameters: In-Vivo and In-Silico …

C Nwonuma, BO Olajide, B Afolabi… - … and Business for …, 2024 - ieeexplore.ieee.org
Drugs and other substances with psychoactive substances have the potential to alter body
functioning and structure when ingested either for medical or recreational purposes. The …

Alkaline Phosphatase Stimulation

IA Ross - Plant-Based Therapeutics, Volume 1: Cannabis sativa, 2023 - Springer
Alkaline phosphatase (AP) emerged after the discovery of a phosphatase abundantly
expressed in prostate tissue that featured an acidic pH optimum. The role of alkaline …