Recent advances in cancer immunotherapy using monoclonal antibodies have dramatically
revolutionized the therapeutic strategy against advanced malignancies, inspiring the …

NK cells are the major lymphocyte subset of the innate immune system that mediates
antiviral and anti-tumor responses. It is well established that they develop mechanisms to …

Summary Many SARS-CoV-2-infected individuals remain asymptomatic. Little is known
about the extent and quality of their antiviral humoral response. Here, we analyze antibody …

Over the last 60 years an eclectic collection of microbes has been tested in a variety of pre-
clinical models as anti-cancer agents. At the forefront of this research are a number of virus …

Gram-positive organisms with their thick envelope cannot be lysed by complement alone.
Nonetheless, antibody-binding on the surface can recruit complement and mark these …

A single dose of human papillomavirus (HPV) vaccine against HPV infection (prerequisite
for cervical cancer) appears to be as efficacious as two or three doses, despite inducing …

Engineered natural killer (NK) cells represent a promising option for immune therapy option
due to their immediate availability in allogeneic settings. Severe acute diseases, such as …

Virus-neutralizing antibodies are a severe obstacle in oncolytic virotherapy. Here, we
present a strategy to convert this unfavorable immune response into an anticancer …

Neutrophil extracellular traps (NETs) are networks of extracellular chromosomal DNA fibers,
histones, and cytoplasmic granule proteins. The release of NET components from …

NK cells contribute to early defenses against viruses through their inborn abilities that
include sensing of PAMPs and inflammatory signals such as cytokines or chemokines …