The simple and efficient conversion of carbonyl compounds into functionalized alkanes via
deoxygenation is highly enabling in chemical synthesis. This Review covers the recent …

[1, 2]-Phospha-Brook rearrangement entails the generation of α-oxygenated carbanions via
the umpolung process. Recently, these anionic species have been widely utilized for several …

We present a new, unified approach for the transformation of benzylic and allylic alcohols,
aldehydes, and ketones into boronic esters under electroreductive conditions. Key to our …

Direct, economical, and green synthesis of deuterated α-amino phosphine oxides remains
an elusive challenge in synthetic chemistry. Herein, we report a visible-light-driven …

Defluorinative manipulation of polyfluorinated molecules has shown great promise due to its
granting of synthetic versatility to inert C− F bonds. The development of chemo‐, stereo‐and …

We describe a photo‐induced reaction for the in situ generation of highly reactive alkyl diazo
species from carbonyl precursors via photo‐excitation of N‐tosylhydrazone anions. The …

Deoxygenative difunctionalization of carbonyls represents a convenient route to construct
complex molecules considering the readily available aldehyde and ketone compounds. The …

Reactivity umpolung is an important concept in organic chemistry. Established reactivity
umpolung mainly focuses on the aldehyde and umpolung of amide carbonyl group is not …

Hydrogen bonds (H-bonds) in energetic compounds have a very pronounced effect on
physicochemical properties such as density, thermal stability, sensitivity, and solubility. Now …

Umpolung is an old and important concept in organic chemistry, which significantly expands
the chemical space and provides unique structures. While, previous research focused on …