The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications
Z Hu, D Ma - Cancer medicine, 2018 - Wiley Online Library
Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
Molecular approaches for HPV genotyping and HPV-DNA physical status
D Tsakogiannis, C Gartzonika… - Expert reviews in …, 2017 - cambridge.org
Persistent infection with high-risk human papillomavirus (HPV) genotypes is the leading
cause of cervical cancer development. To this end several studies have focused on …
cause of cervical cancer development. To this end several studies have focused on …
Diagnosis of sepsis with cell-free DNA by next-generation sequencing technology in ICU patients
Y Long, Y Zhang, Y Gong, R Sun, L Su, X Lin… - Archives of Medical …, 2016 - Elsevier
Background and Aims Bacteremia is a common serious manifestation of disease in the
intensive care unit (ICU), which requires quick and accurate determinations of pathogens to …
intensive care unit (ICU), which requires quick and accurate determinations of pathogens to …
[HTML][HTML] Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck …
RI Haddad, TY Seiwert, LQM Chow… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background To characterize genomic determinants of response to pembrolizumab in
recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) in the …
recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) in the …
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
We study a patient with the human papilloma virus (HPV)-2-driven" tree-man" phenotype
and two relatives with unusually severe HPV4-driven warts. The giant horns form an HPV-2 …
and two relatives with unusually severe HPV4-driven warts. The giant horns form an HPV-2 …
A NGS-based blood test for the diagnosis of invasive HPV-associated carcinomas with extensive viral genomic characterization
Purpose: Use of circulating tumor DNA (ctDNA) for diagnosis is limited regarding the low
number of target molecules in early-stage tumors. Human papillomavirus (HPV)–associated …
number of target molecules in early-stage tumors. Human papillomavirus (HPV)–associated …
Comprehensive genomic profiling of metastatic squamous cell carcinoma of the anal canal
Squamous cell carcinoma of the anal canal (SCCA) is a rare gastrointestinal malignancy
with an increasing annual incidence globally. The majority of cases are linked to prior …
with an increasing annual incidence globally. The majority of cases are linked to prior …
Divergent viral presentation among human tumors and adjacent normal tissues
We applied a newly developed bioinformatics system called VirusScan to investigate the
viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types …
viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types …
Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer
S Desai, B Dharavath, S Manavalan, A Rane… - NAR …, 2022 - academic.oup.com
Persistent pathogen infection is a known cause of malignancy, although with sparse
systematic evaluation across tumor types. We present a comprehensive landscape of 1060 …
systematic evaluation across tumor types. We present a comprehensive landscape of 1060 …
ViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancer
The integration of viral sequences into the host genome is an important driver of
tumorigenesis in many viral mediated cancers, notably cervical cancer and hepatocellular …
tumorigenesis in many viral mediated cancers, notably cervical cancer and hepatocellular …