Impact of airborne particulate matter on skin: A systematic review from epidemiology to in vitro studies

IM Dijkhoff, B Drasler, BB Karakocak… - Particle and fibre …, 2020 - Springer
Background Air pollution is killing close to 5 million people a year, and harming billions
more. Air pollution levels remain extremely high in many parts of the world, and air pollution …

Recent advances in body-on-a-chip systems

JH Sung, YI Wang, N Narasimhan Sriram… - Analytical …, 2018 - ACS Publications
Microphysiological systems (MPS, also known as “organ-on-a-chip”,“body-on-a-chip”, or
“human-on-a-chip”) have emerged over the last 15 years as attractive systems to probe …

Cryomicroneedles for transdermal cell delivery

H Chang, SWT Chew, M Zheng, DCS Lio… - Nature Biomedical …, 2021 - nature.com
Cell therapies for the treatment of skin disorders could benefit from simple, safe and efficient
technology for the transdermal delivery of therapeutic cells. Conventional cell delivery by …

The 3D bioprinted scaffolds for wound healing

PE Antezana, S Municoy, MI Álvarez-Echazú… - Pharmaceutics, 2022 - mdpi.com
Skin tissue engineering and regeneration aim at repairing defective skin injuries and
progress in wound healing. Until now, even though several developments are made in this …

Innovative human three-dimensional tissue-engineered models as an alternative to animal testing

P Bédard, S Gauvin, K Ferland, C Caneparo, È Pellerin… - Bioengineering, 2020 - mdpi.com
Animal testing has long been used in science to study complex biological phenomena that
cannot be investigated using two-dimensional cell cultures in plastic dishes. With time, it …

Modelling the complexity of human skin in vitro

E Hofmann, A Schwarz, J Fink, LP Kamolz, P Kotzbeck - Biomedicines, 2023 - mdpi.com
The skin serves as an important barrier protecting the body from physical, chemical and
pathogenic hazards as well as regulating the bi-directional transport of water, ions and …

Organ-on-a-chip engineering: Toward bridging the gap between lab and industry

Q Ramadan, M Zourob - Biomicrofluidics, 2020 - pubs.aip.org
Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …

Human in vitro skin models for wound healing and wound healing disorders

E Hofmann, J Fink, AL Pignet, A Schwarz… - Biomedicines, 2023 - mdpi.com
Skin wound healing is essential to health and survival. Consequently, high amounts of
research effort have been put into investigating the cellular and molecular components …

Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering

NR Barros, HJ Kim, MJ Gouidie, KJ Lee… - …, 2021 - iopscience.iop.org
The skin serves a substantial number of physiological purposes and is exposed to
numerous biological and chemical agents owing to its large surface area and accessibility …

Stem cells for next level toxicity testing in the 21st century

E Fritsche, T Haarmann‐Stemmann, J Kapr, S Galanjuk… - Small, 2021 - Wiley Online Library
The call for a paradigm change in toxicology from the United States National Research
Council in 2007 initiates awareness for the invention and use of human‐relevant alternative …