Retinal and corneal changes associated with intraocular silicone oil tamponade

M Ferrara, G Coco, T Sorrentino, KM Jasani… - Journal of Clinical …, 2022 - mdpi.com
Silicone oils (SO) are used as long-term intraocular tamponades and have an irreplaceable
role in vitreoretinal surgery. They can, however, be associated with multiple and potentially …

Progress in Wound-Healing Products Based on Natural Compounds, Stem Cells, and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets …

GK Srivastava, S Martinez-Rodriguez, NI Md Fadilah… - Polymers, 2024 - mdpi.com
Wounds are breaks in the continuity of the skin and underlying tissues, resulting from
external causes such as cuts, blows, impacts, or surgical interventions. Countless …

Metal–organic frameworks as drug delivery platforms for ocular therapeutics

J Gandara-Loe, I Ortuño-Lizarán… - … applied materials & …, 2018 - ACS Publications
Metal–organic frameworks (MOFs) have been evaluated as potential nanocarriers for
intraocular incorporation of brimonidine tartrate to treat chronic glaucoma. Experimental …

Current situation and challenges in vitreous substitutes

C Mondelo‐García, E Bandín‐Vilar… - Macromolecular …, 2021 - Wiley Online Library
Vitreo‐retinal disorders constitute a significant portion of treatable ocular diseases. These
pathologies often require vitreo‐retinal surgery and, as a consequence, the use of vitreous …

Interfacial dynamics of adsorption layers as supports for biomedical research and diagnostics

E Santini, I Nepita, AG Bykov, F Ravera, L Liggieri… - Colloids and …, 2022 - mdpi.com
The input of chemical and physical sciences to life sciences is increasingly important.
Surface science as a complex multidisciplinary research area provides many relevant …

Comparative study of chemical composition, molecular and rheological properties of silicone oil medical devices

R Mendichi, AG Schieroni, D Piovani… - … Vision Science & …, 2019 - tvst.arvojournals.org
Purpose: We evaluated chemical composition, and molecular and rheological properties in
10 commercially available silicone oils (SilOils), focusing on siloxane chains of low …

Safety of silicone oils as intraocular medical device: An in vitro cytotoxicity study

MR Romano, M Ferrara, C Gatto, L Giurgola… - Experimental Eye …, 2020 - Elsevier
This study aimed to assess the cytotoxic effect of low molecular weight components (LMWC)
and conventional silicone oils (SOs) 1000 cSt with different degree of purification (raw …

Ex vivo evaluation of retinal cytotoxicity after the use of multiple medical devices in pars plana vitrectomy in porcine eyes

C Gatto, MR Romano, L Giurgola, M Ferrara… - Experimental Eye …, 2021 - Elsevier
This study aimed to evaluate viability of retinal cells after the use of multiple intraoperative
devices, namely a vitreal dye (triamcinolone acetonide, TA), a ERM/ILM dye (solution of …

Intraocular emulsion of silicone oil (ITEMS) grading system: an evidence-based expert-led consensus

MR Romano, M Ferrara, RM Coco-Martin, A Rickmann… - Retina, 2023 - journals.lww.com
Purpose: To propose the InTraocular EMulsion of Silicone oil (ITEMS) grading system for the
assessment of silicone oil (SiO) emulsion, applicable in a routine clinical setting and …

Silicone oils compared and found wanting

DHW Steel, D Wong, T Sakamoto - Graefe's Archive for Clinical and …, 2021 - Springer
Silicone oil was first introduced in the treatment of retinal detachment (RD) by Cibis in the
1960s and approved by the US Food and Drug Administration for intraocular use in 1994 [1] …