Understanding and interpreting community sequencing measurements of the vaginal microbiome

HL Berman, MR McLaren… - BJOG: An International …, 2020 - Wiley Online Library
Community‐wide high‐throughput sequencing has transformed the study of the vaginal
microbiome, and clinical applications are on the horizon. Here we outline the three main …

Intramuscular therapeutic doses of enrofloxacin affect microbial community structure but not the relative abundance of fluoroquinolones resistance genes in swine …

X Li, X Tang, M Chen, S Wang, C Tong, J Xu… - Science of The Total …, 2024 - Elsevier
Livestock manure is a major source of veterinary antibiotics and antibiotic resistance genes
(ARGs). Elucidation of the residual characteristics of ARGs in livestock manure following the …

Comparisons of plasma and fecal pharmacokinetics of danofloxacin and enrofloxacin in healthy and Mannheimia haemolytica infected calves

AF Beyi, JP Mochel, G Magnin, T Hawbecker… - Scientific reports, 2022 - nature.com
Danofloxacin and enrofloxacin are fluoroquinolones (FQs) used to treat and control bovine
respiratory disease (BRD) complex. While low toxicity, high bactericidal activity, and …

[HTML][HTML] Longitudinal effects of enrofloxacin or tulathromycin use in preweaned calves at high risk of bovine respiratory disease on the shedding of antimicrobial …

RV Pereira, C Altier, JD Siler, S Mann, D Jordan… - Journal of dairy …, 2020 - Elsevier
The objective of this study was to longitudinally quantify Escherichia coli resistant to
ciprofloxacin and ceftriaxone in calves treated with enrofloxacin or tulathromycin for the …

Danofloxacin treatment alters the diversity and resistome profile of gut microbiota in calves

AF Beyi, D Brito-Goulart, T Hawbecker, C Slagel… - Microorganisms, 2021 - mdpi.com
Fluoroquinolones, such as danofloxacin, are used to control bovine respiratory disease
complex in beef cattle; however, little is known about their effects on gut microbiota and …

Influence of Single Dose Enrofloxacin Injection on Development of Fluoroquinolone Resistance in Campylobacter jejuni in Calves

DB Goulart, AF Beyi, Z Wu, MC Adiguzel, S Wilson… - Antibiotics, 2022 - mdpi.com
Fluoroquinolone (FQ) resistance in a major foodborne bacterial pathogen, Campylobacter
jejuni, derived from cattle has recently become prevalent and poses a significant public …

Enrofloxacin alters fecal microbiota and resistome irrespective of its dose in calves

AF Beyi, D Brito-Goulart, T Hawbecker, B Ruddell… - Microorganisms, 2021 - mdpi.com
Enrofloxacin is a fluoroquinolone drug used to prevent and control bovine respiratory
disease (BRD) complex in multiple or single doses, ranging from 7.5 to 12.5 mg/kg body …

Effects of danofloxacin dosing regimen on gastrointestinal pharmacokinetics and fecal microbiome in steers

JL Halleran, BJ Callahan, ME Jacob, HJ Sylvester… - Scientific Reports, 2021 - nature.com
Fluoroquinolones are a class of antimicrobial commonly used in human medicine, and
deemed critical by the World Health Organization. Nonetheless, two formulations are …

Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers

DM Foster, ME Jacob, KA Farmer, BJ Callahan… - PLoS …, 2019 - journals.plos.org
Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial
resistance in enteric bacteria. Our objective was to determine the concentration of ceftiofur …

[HTML][HTML] The effects of cyclosporine A or activated charcoal co-administration on the pharmacokinetics of enrofloxacin in chickens

T Petkova, A Milanova, B Poźniak - Poultry Science, 2023 - Elsevier
The study aimed to investigate the possible role of efflux transporter proteins in the
pharmacokinetics of enrofloxacin (ENR) in broilers in the model of co-administration of …