The growing synthetic utility of the Weinreb amide

S Balasubramaniam, IS Aidhen - Synthesis, 2008 - thieme-connect.com
Abstract N-Methoxy-N-methylamide, popularly addressed as the Weinreb amide, has
surfaced as an amide with a difference. This amide has served as an excellent acylating …

Nanocellulose as a Reaction Media and Stoichiometric Reagent for FeCl3-Mediated Reductive Functionalization of Nitro Compounds

S Mkrtchyan, VB Purohit, J Zapletal… - ACS Sustainable …, 2023 - ACS Publications
Among a wide array of synthetic amides, N-aryl/alkyl amides are an important class of
structural motifs having significant importance in pharmaceutical and agrochemical …

Microwave-Assisted Synthesis of Weinreb and MAP Aryl Amides via Pd-Catalyzed Heck Aminocarbonylation Using Mo(CO)6 or W(CO)6

A Wieckowska, R Fransson, LR Odell… - The Journal of Organic …, 2011 - ACS Publications
A simple and expedient process for the Heck aminocarbonylative synthesis of Weinreb and
MAP amide acylating agents, from aryl halides, is reported. This methodology utilizes solid …

Convenient method for the preparation of weinreb amides via Pd-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure

JR Martinelli, DMM Freckmann, SL Buchwald - Organic letters, 2006 - ACS Publications
Convenient Method for the Preparation of Weinreb Amides via Pd-Catalyzed Aminocarbonylation
of Aryl Bromides at Atmospheric Pressure | Organic Letters ACS ACS Publications C&EN CAS …

Transition metal-mediated annulation approaches for synthesis of arylnaphthalene lignan lactones

S Park, JH Kim, SH Kim, D Shin - Frontiers in Chemistry, 2020 - frontiersin.org
Arylnaphthalene lignan lactones belong to a class of natural lignans, and more than 60
analogs have been isolated. Their pharmacological activities as well as unique structural …

Synthesis of Biaryls via Palladium‐Catalyzed [2+2+2] Cocyclization of Arynes and Diynes: Application to the Synthesis of Arylnaphthalene Lignans

Y Sato, T Tamura, A Kinbara… - Advanced Synthesis & …, 2007 - Wiley Online Library
A novel method for construction of biaryls via palladium (0)‐catalyzed [2+ 2+ 2] cocyclization
of diynes and arynes was developed. By this [2+ 2+ 2] cocyclization, various …

An Efficient synthesis of Weinreb amides and ketones via palladium nanoparticles on ZIF-8 catalysed carbonylative coupling

TT Dang, A Chen, AM Seayad - RSC Advances, 2014 - pubs.rsc.org
Heterogeneously catalysed carbonylative coupling reactions such as aminocarbonylation
and Suzuki-carbonylation are reported using Pd nanoparticles supported on ZIF-8 for …

One-pot amidation of olefins through Pd-catalyzed coupling of alkylboranes and carbamoyl chlorides

Y Yasui, S Tsuchida, H Miyabe… - The Journal of Organic …, 2007 - ACS Publications
A one-pot synthesis of C1-elongated amides starting from olefins and carbamoyl chlorides
has been developed. Alkylboranes, generated by hydroboration of terminal olefins with 9 …

N-Methoxy-N-methylcyanoformamide, a Highly Reactive Reagent for the Formation of β-Keto Weinreb Amides and Unsymmetrical Ketones

J Nugent, BD Schwartz - Organic letters, 2016 - ACS Publications
A rapid and straightforward synthesis of the new and highly reactive reagent N-methoxy-N-
methylcyanoformamide from trimethylsilyl cyanide and N-methoxy-N …

Synthesis of Weinreb amides via Pd-catalyzed aminocarbonylation of heterocyclic-derived triflates

A Deagostino, P Larini, EG Occhiato… - The Journal of …, 2008 - ACS Publications
The direct transformation of lactam-, lactone-, and thiolactone-derived triflates into N-
methoxy-N-methyl or morpholine Weinreb amides has been realized using Pd-catalyzed …