Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

Immune mechanisms in pulmonary fibrosis

S Kolahian, IE Fernandez, O Eickelberg… - American journal of …, 2016 - atsjournals.org
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, represents a chronic and
progressive disease with high mortality and limited therapeutic options. Excessive …

Regulation of epithelial transitional states in murine and human pulmonary fibrosis

F Wang, C Ting, KA Riemondy… - The Journal of …, 2023 - Am Soc Clin Investig
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease arising from impaired
regeneration of the alveolar epithelium after injury. During regeneration, type 2 alveolar …

Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model

M Selman, A Pardo - American journal of respiratory and critical …, 2014 - atsjournals.org
A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …

Immune mechanisms of pulmonary fibrosis with bleomycin

Y Ishida, Y Kuninaka, N Mukaida, T Kondo - International journal of …, 2023 - mdpi.com
Fibrosis and structural remodeling of the lung tissue can significantly impair lung function,
often with fatal consequences. The etiology of pulmonary fibrosis (PF) is diverse and …

Molecular and cellular mechanisms of pulmonary fibrosis

NW Todd, IG Luzina, SP Atamas - Fibrogenesis & tissue repair, 2012 - Springer
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

The pathogenesis of pulmonary fibrosis: a moving target

WA Wuyts, C Agostini, KM Antoniou… - European …, 2013 - Eur Respiratory Soc
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung …

[HTML][HTML] Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis

N Sakai, AM Tager - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2013 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is characterized by the progressive and ultimately fatal
accumulation of fibroblasts and extracellular matrix in the lung that distorts its architecture …

The epithelium in idiopathic pulmonary fibrosis: breaking the barrier

A Camelo, R Dunmore, MA Sleeman… - Frontiers in …, 2014 - frontiersin.org
Idiopathic pulmonary fibrosis is a progressive disease of unknown etiology characterized by
a dysregulated wound healing response that leads to fatal accumulation of fibroblasts and …

The pathogenesis of idiopathic pulmonary fibrosis

WR Coward, G Saini, G Jenkins - Therapeutic advances in …, 2010 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an appalling
prognosis. The failure of anti-inflammatory therapies coupled with the observation that …