Recent Progress in Metal-Free Direct Synthesis of Imidazo[1,2-a]pyridines

V Kurteva - ACS omega, 2021 - ACS Publications
This Mini-Review highlights the most effective protocols for metal-free direct synthesis of
imidazo [1, 2-a] pyridines, crucial target products and key intermediates, developed in the …

Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review

J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …

The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

C Martini, MID Mardjan, A Basso - Beilstein Journal of Organic …, 2024 - beilstein-journals.org
Abstract The Groebke–Blackburn–Bienaymé (GBB) three-component reaction, discovered in
1998, is a very efficient strategy to assemble imidazo [1, 2-a]-heterocycles starting from …

Diaza-1, 3-butadienes as useful intermediate in heterocycles synthesis

J Heredia-Moya, DA Zurita, JE Cadena-Cruz… - Molecules, 2022 - mdpi.com
Many heterocyclic compounds can be synthetized using diaza-1, 3-butadienes (DADs) as
key structural precursors. Isolated and in situ diaza-1, 3-butadienes, produced from their …

Potassium dihydrogen phosphate‐catalyzed synthesis of benzylpyrazolyl coumarin and pyrano [2,3‐c] pyrazole derivatives via cascade—One‐pot—Multicomponent …

S Mathavan, RBRD Yamajala - Journal of Heterocyclic …, 2023 - Wiley Online Library
A simple one‐pot protocol for the synthesis of benzylpyrazolyl coumarin and pyrano [2, 3‐c]
pyrazole derivatives in the presence of potassium dihydrogen phosphate (KH2PO4) has …

Copper (I) Catalysed Tandem C− C and C− N Bond Cleavage of N‐Fused Imidazoles towards the Synthesis of N‐pyridinylamides

F Ahmad Sofi, MH Masoodi, M Ovais Dar… - …, 2023 - Wiley Online Library
Copper (I) catalysed oxidative conversion of imidazopyridines into N‐pyridinylamides has
been achieved via tandem C− C and C− N bond cleavages under oxidative reaction …

A sustainable and scalable multicomponent continuous flow process to access fused imidazoheterocycle pharmacophores

BJM Baker, WJ Kerr, DM Lindsay, VK Patel… - Green …, 2021 - pubs.rsc.org
Described herein is a green, continuous flow process for the synthesis of various
aminoimidazoheterocycles, through the Gröebke–Blackburn–Bienaymé reaction (GBBR) …

Efficient synthesis of glycosylated imidazo [1, 2-a] pyridines via solvent catalysed Groebke-Blackburn-Bienayme reaction

B Shankar, B Kumar, S Kumar, A Arora, R Tomar… - Carbohydrate …, 2023 - Elsevier
A solvent catalysed and metal catalyst-free Groebke-Blackburn-Bienayame three
component reaction (GBB-3CR) has been developed for the synthesis of 2-(β-D-glycal-1-yl) …

Synthesis of Fused Imidazoles and Pyrimidinones from 2‐Aminoazines

Y Wang, M Jiang, B Liu, W Xianzhang… - Asian Journal of …, 2024 - Wiley Online Library
Fused imidazole and pyrimidine heterocycles represent two important classes of organic
compounds. Numerous synthetic methods have been developed for the synthesis of these …

Recent Advances of Thiamine in Organic Synthesis

N Zhang, X Yu, Y Zhang - Advanced Synthesis & Catalysis, 2022 - Wiley Online Library
Thiamine (VB1) has been proved to be a powerful biocatalyst for various organic
transformations. VB1 offers several unique advantages, such as economical, non‐toxic …