malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum …

BB Agaba, A Yeka, S Nsobya, E Arinaitwe… - Malaria journal, 2019 - Springer
Background Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a
vital role in improving malaria case management and surveillance particularly in Africa …

Encouraging AWaRe-ness and discouraging inappropriate antibiotic use—the new 2019 Essential Medicines List becomes a global antibiotic stewardship tool

M Sharland, S Gandra, B Huttner, L Moja… - The Lancet Infectious …, 2019 - thelancet.com
Comment www. thelancet. com/infection Vol 19 December 2019 1279 of activity, and
potential for inducing antimicrobial resistance, whereas Reserve antibiotics were selected …

[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

[HTML][HTML] Major threat to malaria control programs by Plasmodium falciparum lacking histidine-rich protein 2, Eritrea

A Berhane, K Anderson, S Mihreteab… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
False-negative results for Plasmodium falciparum histidine-rich protein (HRP) 2–based
rapid diagnostic tests (RDTs) are increasing in Eritrea. We investigated HRP gene 2/3 …

[PDF][PDF] Malaria rapid diagnostic test performance: results of WHO product testing of malaria RDTs: round 8 (2016–2018)

World Health Organization - 2018 - apps.who.int
WHO estimates that 3.2 billion people are at risk for malaria. In 2016, there were an
estimated 216 million new cases (with an uncertainty range of 196 million to 263 million) …

Pfhrp2-Deleted Plasmodium falciparum Parasites in the Democratic Republic of the Congo: A National Cross-sectional Survey

JB Parr, R Verity, SM Doctor, M Janko… - The Journal of …, 2017 - academic.oup.com
Abstract Background. Rapid diagnostic tests (RDTs) account for more than two-thirds of
malaria diagnoses in Africa. Deletions of the Plasmodium falciparum hrp2 (pfhrp2) gene …

High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy

CA Vera-Arias, A Holzschuh, CO Oduma, K Badu… - Elife, 2022 - elifesciences.org
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …

Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya

KB Beshir, N Sepúlveda, J Bharmal, A Robinson… - Scientific reports, 2017 - nature.com
Deletions of the Plasmodium falciparum hrp2 and hrp3 genes can affect the performance of
HRP2-based malaria rapid diagnostic tests (RDTs). Such deletions have been reported from …

Malaria control initiatives that have the potential to be gamechangers in India's quest for malaria elimination

M Rahi, A Sharma - The Lancet Regional Health-Southeast Asia, 2022 - thelancet.com
Malaria continues to have devastating effect on people's lives especially in developing
countries. India is slated for malaria elimination by 2030. Though India has sustained a …