Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays

S Nishizuka, L Charboneau, L Young… - Proceedings of the …, 2003 - National Acad Sciences
Because most potential molecular markers and targets are proteins, proteomic profiling is
expected to yield more direct answers to functional and pharmacological questions than …

Cytomics in predictive medicine

GK Valet, A Tárnok - Cytometry Part B: Clinical Cytometry: The …, 2003 - Wiley Online Library
Patient‐specific, disease‐course predictions with> 95% or> 99% accuracy during therapy
would be highly valuable for everyday medicine. If these predictors were available, disease …

'Omic'and hypothesis-driven research in the molecular pharmacology of cancer

JN Weinstein - Current opinion in pharmacology, 2002 - Elsevier
Given the layered, evolutionary complexity of biological systems, it will not be possible to
understand them comprehensively on the basis of hypothesis-driven research alone …

HLA class I and II genotype of the NCI-60 cell lines

S Adams, FM Robbins, D Chen, D Wagage… - Journal of translational …, 2005 - Springer
Sixty cancer cell lines have been extensively characterized and used by the National
Cancer Institute's Developmental Therapeutics Program (NCI-60) since the early 90's as …

Data mining in genomics

JK Lee, PD Williams, S Cheon - Clinics in laboratory medicine, 2008 - Elsevier
This article reviews important emerging statistical concepts, data mining techniques, and
applications that have been recently developed and used for genomic data analysis. First …

NLProt: extracting protein names and sequences from papers

S Mika, B Rost - Nucleic acids research, 2004 - academic.oup.com
Automatically extracting protein names from the literature and linking these names to the
associated entries in sequence databases is becoming increasingly important for annotating …

[PDF][PDF] Predictive medicine by cytomics: potential and challenges

G Valet - Journal of Biological Regulators and Homeostatic …, 2002 - classimed.de
Predictive medicine by cytomics represents a new concept which provides disease course
predictions for individual patients. The predictive information is derived from the molecular …

Gene expression profiling in hypertension research: a critical perspective

M Pravenec, C Wallace, TJ Aitman, TW Kurtz - Hypertension, 2003 - Am Heart Assoc
Recent advances in molecular biology and technology have made it possible to monitor the
expression levels of virtually all genes simultaneously. As the tools for gene expression …

[PDF][PDF] A hybrid reduction approach for enhancing cancer classification of microarray data

AM Mahmoud, BA Maher - International Journal of advanced research in …, 2014 - Citeseer
This paper presents a novel hybrid machine learning (ML) reduction approach to enhance
cancer classification accuracy of microarray data based on two ML gene ranking techniques …

[图书][B] Nutrigenomics

G Rimbach, J Fuchs - 2005 - taylorfrancis.com
Nutritional genomics, also referred to as nutrigenomics, is considered one of the next
frontiers in the post-genomic era. This book features the latest research on the role of …