Immunobiology of human cytomegalovirus: from bench to bedside
T Crough, R Khanna - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …
and periodically reactivates without causing symptoms in healthy individuals. In the absence …
Aspects of human cytomegalovirus latency and reactivation
M Reeves, J Sinclair - Human Cytomegalovirus, 2008 - Springer
Primary infection of healthy individuals with human cytomegalovirus (HCMV) is usually
asymptomatic and results in the establishment of a lifelong latent infection of the host …
asymptomatic and results in the establishment of a lifelong latent infection of the host …
Defining the transcriptional landscape during cytomegalovirus latency with single-cell RNA sequencing
M Shnayder, A Nachshon, B Krishna, E Poole… - MBio, 2018 - Am Soc Microbiol
Primary infection with human cytomegalovirus (HCMV) results in a lifelong infection due to
its ability to establish latent infection, with one characterized viral reservoir being …
its ability to establish latent infection, with one characterized viral reservoir being …
Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells
KW Boehme, M Guerrero, T Compton - The Journal of Immunology, 2006 - journals.aai.org
Human CMV (HCMV) is a ubiquitous member of the Herpesviridae family and an
opportunistic pathogen that poses significant health risks for immunocompromised patients …
opportunistic pathogen that poses significant health risks for immunocompromised patients …
Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death
Human cytomegalovirus infection perturbs multiple cellular processes that could promote
the release of proapoptotic stimuli. Consequently, it encodes mechanisms to prevent cell …
the release of proapoptotic stimuli. Consequently, it encodes mechanisms to prevent cell …
[HTML][HTML] Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells
CC Rossetto, M Tarrant-Elorza, GS Pari - PLoS pathogens, 2013 - journals.plos.org
The parameters involved in human cytomegalovirus (HCMV) latent infection in CD14 (+) and
CD34 (+) cells remain poorly identified. Using next generation sequencing we deduced the …
CD34 (+) cells remain poorly identified. Using next generation sequencing we deduced the …
Selection of T cell clones expressing high-affinity public TCRs within human cytomegalovirus-specific CD8 T cell responses
L Trautmann, M Rimbert, K Echasserieau… - The Journal of …, 2005 - journals.aai.org
Assessment of clonal diversity of T cell responses against human CMV (HCMV), a major
cause of morbidity in immunodepressed patients, provides important insights into the …
cause of morbidity in immunodepressed patients, provides important insights into the …
[HTML][HTML] High prevalence of human cytomegalovirus proteins and nucleic acids in primary breast cancer and metastatic sentinel lymph nodes
C Taher, J de Boniface, AA Mohammad, P Religa… - PloS one, 2013 - journals.plos.org
Background Breast cancer is a leading cause of death among women worldwide. Increasing
evidence implies that human cytomegalovirus (HCMV) infection is associated with several …
evidence implies that human cytomegalovirus (HCMV) infection is associated with several …
[HTML][HTML] HCMV latency: what regulates the regulators?
E Elder, J Sinclair - Medical microbiology and immunology, 2019 - Springer
Human cytomegalovirus (HCMV) latency and reactivation is regulated by the chromatin
structure at the major immediate early promoter (MIEP) within myeloid cells. Both cellular …
structure at the major immediate early promoter (MIEP) within myeloid cells. Both cellular …
Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis
Clinical and low passage strains of human CMV (HCMV) encode an additional MHC class I-
related molecule UL142, in addition to the previously described UL18. The UL142 open …
related molecule UL142, in addition to the previously described UL18. The UL142 open …