The critical issue linking lipids and inflammation: Clinical utility of stopping oxidative stress

BF Bale, AL Doneen, PP Leimgruber… - Frontiers in …, 2022 - frontiersin.org
The formation of an atheroma begins when lipoproteins become trapped in the intima.
Entrapped lipoproteins become oxidized and activate the innate immune system. This …

Cut stroke in half: polypill for primary prevention in stroke

M Brainin, V Feigin, S Martins, K Matz… - … Journal of Stroke, 2018 - journals.sagepub.com
This review summarizes the potential for polypill therapies for stroke prevention. While a
number of studies applying different approaches regarding polypill have been performed …

A population-based screening study for cardiovascular diseases and diabetes in Danish postmenopausal women: acceptability and prevalence

M Dahl, L Frost, R Søgaard, IC Klausen… - BMC cardiovascular …, 2018 - Springer
Background Reducing women's cardiovascular risk and the economic costs associated with
cardiovascular diseases (CVD) and diabetes (DM) continues to be a challenge. Whether a …

Association between non‐high‐density lipoprotein cholesterol levels and asymptomatic vulnerable carotid atherosclerotic plaques

J Wu, J Zhang, A Wang, S Chen, S Wu… - European Journal of …, 2019 - Wiley Online Library
Background and purpose Carotid atherosclerosis, especially rupture of plaques, is related to
cerebrovascular diseases. Non‐high‐density lipoprotein cholesterol (non‐HDL‐C) is …

[HTML][HTML] Precision healthcare of type 2 diabetic patients through implementation of haptoglobin genotyping

BF Bale, AL Doneen, DJ Vigerust - Frontiers in Cardiovascular …, 2018 - frontiersin.org
It is well recognized that there is a need for medicine to migrate to a platform of delivering
preventative care based on an individual's genetic make-up. The term, which encompasses …

[PDF][PDF] Beneficial effects of pre-stroke statins use in cardioembolic stroke patients with atrial fibrillation: a hospital-based retrospective analysis

D Kotlęga, M Gołąb-Janowska, A Meller… - Archives of Medical …, 2019 - termedia.pl
Results Patients from the non-statin group had greater initial and discharge NIHSS scores
(10 vs. 11.9, probability value p< 0.05; 7.6 vs. 9.5, p< 0.05 respectively). The improvement in …

[PDF][PDF] Effects and potential mechanism of atorvastatin treatment on Lp-PLA2 in rats with dyslipidemia

D Zheng, A Cai, R Xu, Z Mai, Y Zhou, F Zeng… - Archives of Medical …, 2018 - termedia.pl
Results Compared to the normal-control group, fasting plasma total cholesterol (TC) and low-
density lipoprotein cholesterol (LDL-C) levels were significantly increased in dyslipidemia …

[PDF][PDF] Three-dimensional ultrasonographic evaluation of carotid artery plaque surface irregularity

H Artas, I Okcesiz - Archives of Medical Science, 2019 - termedia.pl
Results 3D imaging was successfully performed in 45 of the 50 cases and the technical
success rate was 90%. A single plaque was detected in 64.4% of the patients, with the …

[HTML][HTML] Microvascular disease confers additional risk to COVID-19 infection

BF Bale, AL Doneen, DJ Vigerust - Medical hypotheses, 2020 - Elsevier
The majority of fatalities thus far in the COVID-19 pandemic have been attributed to
pneumonia. As expected, the fatality rate reported in China is higher in people with chronic …

Cardiovascular prevention: migrating from a binary to a ternary classification

AL Doneen, BF Bale, DJ Vigerust… - Frontiers in …, 2020 - frontiersin.org
Migrating from a binary approach to risk assessment to a ternary model of disease
identification allows for individualized, optimal disease management. Redefining the …