Methods of integrating data to uncover genotype–phenotype interactions

MD Ritchie, ER Holzinger, R Li… - Nature Reviews …, 2015 - nature.com
Recent technological advances have expanded the breadth of available omic data, from
whole-genome sequencing data, to extensive transcriptomic, methylomic and metabolomic …

What is the association between sedentary behaviour and cognitive function? A systematic review

RS Falck, JC Davis, T Liu-Ambrose - British journal of sports medicine, 2017 - bjsm.bmj.com
Aim The increasing rate of all-cause dementia worldwide and the lack of effective
pharmaceutical treatments emphasise the value of lifestyle approaches as prevention …

[HTML][HTML] Pregnancy outcomes and vaccine effectiveness during the period of omicron as the variant of concern, INTERCOVID-2022: a multinational, observational …

J Villar, CPS Conti, RB Gunier, S Ariff, R Craik… - The Lancet, 2023 - thelancet.com
Background In 2021, we showed an increased risk associated with COVID-19 in pregnancy.
Since then, the SARS-CoV-2 virus has undergone genetic mutations. We aimed to examine …

[HTML][HTML] Mechanical or biologic prostheses for aortic-valve and mitral-valve replacement

AB Goldstone, P Chiu, M Baiocchi… - … England Journal of …, 2017 - Mass Medical Soc
Background In patients undergoing aortic-valve or mitral-valve replacement, either a
mechanical or biologic prosthesis is used. Biologic prostheses have been increasingly …

Assessment of remote heart rhythm sampling using the AliveCor heart monitor to screen for atrial fibrillation: the REHEARSE-AF study

JPJ Halcox, K Wareham, A Cardew, M Gilmore… - Circulation, 2017 - Am Heart Assoc
Background: Asymptomatic atrial fibrillation (AF) is increasingly common in the aging
population and implicated in many ischemic strokes. Earlier identification of AF with …

Circulating tumor DNA dynamics predict benefit from consolidation immunotherapy in locally advanced non-small-cell lung cancer

EJ Moding, Y Liu, BY Nabet, JJ Chabon… - Nature Cancer, 2020 - nature.com
Circulating tumor DNA (ctDNA) molecular residual disease (MRD) following curative-intent
treatment strongly predicts recurrence in multiple tumor types, but whether further treatment …

Effect of a pharmacist-led educational intervention on inappropriate medication prescriptions in older adults: the D-PRESCRIBE randomized clinical trial

P Martin, R Tamblyn, A Benedetti, S Ahmed… - Jama, 2018 - jamanetwork.com
Importance High rates of inappropriate prescribing persist among older adults in many
outpatient settings, increasing the risk of adverse drug events and drug-related …

Sample size determination: A practical guide for health researchers

A Althubaiti - Journal of General and Family Medicine, 2023 - Wiley Online Library
Although sample size calculations play an essential role in health research, published
research often fails to report sample size selection. This study aims to explain the …

[PDF][PDF] Determination of sample size and sampling methods in applied research

TS Nanjundeswaraswamy, S Divakar - Proceedings on engineering …, 2021 - academia.edu
Sample size, sampling method and sampling technique plays a major role in social
sciences, business, health science, agricultural science research and survey research. If the …

[图书][B] Sample size determination and power

TP Ryan - 2013 - books.google.com
A comprehensive approach to sample size determination and power with applications for a
variety of fields Sample Size Determination and Power features a modern introduction to the …