Pioneering electron microscopy studies defined two primary populations of ribosomes in
eukaryotic cells: one freely dispersed through the cytoplasm and the other bound to the …

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue.
Similar but distinct versions of the N-end rule operate in all organisms examined, from …

The genetic code is degenerate. Each amino acid is encoded by up to six synonymous
codons; the choice between these codons influences gene expression. Here, we show that …

We have characterized the structure and function of RNA sequences that direct beta-
cytoplasmic actin mRNA to the cell periphery were mapped to two segments of 3' …

In recent years, better instrumentation and greater computing power have enabled the
imaging of elusive biomolecule dynamics in cells, driving many advances in understanding …

The N‐end rule relates the in vivo half‐life of a protein to the identity of its N‐terminal
residue. Similar but distinct versions of the N‐end rule operate in all organisms examined …

Certain stress conditions can induce cleavage of tRNAs around the anticodon loop via the
use of the ribonuclease angiogenin. The cellular factors that regulate tRNA cleavage are not …

The N-end rule relates the in vivo half-life I of a protein to the identity of its N-terminal residue
(Varshavsky 1992). Similar but distinct versions of the N-end rule have been shown to …

Although aminoacyl-tRNA synthetases (ARSs) are housekeeping enzymes essential for
protein synthesis, they can play non-catalytic roles in diverse biological processes. Some …

This review offers a comprehensive analysis of eukaryotic translation elongation factor 1
(eEF-1α) in comparison with its bacterial counterpart EF-Tu. Altogether, the data presented …