Raman spectroscopy and chemometrics: A potential universal method for diagnosing cancer

NM Ralbovsky, IK Lednev - Spectrochimica Acta Part A: Molecular and …, 2019 - Elsevier
Cancer is the second-leading cause of death worldwide. It affects an unfathomable number
of people, with almost 16 million Americans currently living with it. While many cancers can …

Applications of Raman spectroscopy in clinical medicine

Y Qi, EX Chen, D Hu, Y Yang, Z Wu, M Zheng… - Food …, 2024 - Wiley Online Library
Raman spectroscopy is a nondestructive and highly effective technique for analyzing
biological tissues and diagnosing diseases by providing detailed spectral information about …

Raman spectroscopy in chronic heart failure diagnosis based on human skin analysis

YA Khristoforova, LA Bratchenko… - Journal of …, 2023 - Wiley Online Library
This work aims at studying Raman spectroscopy in combination with chemometrics as an
alternative fast noninvasive method to detect chronic heart failure (CHF) cases. Optical …

Label-free, rapid and highly accurate identification and categorization of leukemia cells via Raman spectroscopy

L Jiang, MX Ren, G Niu, J Shi, X Cao, Y Duan… - Sensors and Actuators B …, 2023 - Elsevier
Leukemia, a highly malignant form of cancer, relies on early diagnosis for effective treatment
and patient survival. Currently, leukemia is diagnosed by manually identifying blood cells …

A droplet-based microfluidic chip as a platform for leukemia cell lysate identification using surface-enhanced Raman scattering

M Hassoun, J Rüger, T Kirchberger-Tolstik… - Analytical and …, 2018 - Springer
A new approach is presented for cell lysate identification which uses SERS-active silver
nanoparticles and a droplet-based microfluidic chip. Eighty-nanoliter droplets are generated …

Raman spectroscopy and artificial intelligence to predict the Bayesian probability of breast cancer

R Kothari, V Jones, D Mena, V Bermúdez Reyes… - Scientific reports, 2021 - nature.com
This study addresses the core issue facing a surgical team during breast cancer surgery:
quantitative prediction of tumor likelihood including estimates of prediction error. We have …

Spectral model for diagnosis of acute leukemias in whole blood and plasma through Raman spectroscopy

AM da Silva, FSA de Siqueira e Oliveira… - Journal of …, 2018 - spiedigitallibrary.org
Acute leukemias are oncohematological diseases that compromise the bone marrow and
have a complex diagnostic definition, leading to a high mortality when diagnosed late. This …

Rapid and non-invasive discrimination of acute leukemia bone marrow supernatants by Raman spectroscopy and multivariate statistical analysis

H Liang, X Cheng, S Dong, H Wang, E Liu, Y Ru… - … of Pharmaceutical and …, 2022 - Elsevier
A simple and non-invasive detection method for acute myeloid leukemia (AML) and acute
lymphoblastic leukemia (ALL) was established by systematically investigating the …

New perspectives for viability studies with high-content analysis Raman spectroscopy (HCA-RS)

AS Mondol, N Töpfer, J Rüger, U Neugebauer… - Scientific reports, 2019 - nature.com
Raman spectroscopy has been widely used in clinical and molecular biological studies,
providing high chemical specificity without the necessity of labels and with little-to-no sample …

[HTML][HTML] Label-free molecular imaging of the kidney

BM Prentice, RM Caprioli, V Vuiblet - Kidney international, 2017 - Elsevier
In this review, we will highlight technologies that enable scientists to study the molecular
characteristics of tissues and/or cells without the need for antibodies or other labeling …