Current and Emerging Treatment Options for Multidrug Resistant Escherichia coli Urosepsis: A Review

MM Walker, JA Roberts, BA Rogers, PNA Harris… - Antibiotics, 2022 - mdpi.com
Escherichia coli is a versatile commensal and pathogenic member of the human microflora.
As the primary causative pathogen in urosepsis, E. coli places an immense burden on …

Extensively and multidrug-resistant bacterial strains: case studies of antibiotics resistance

B Almutairy - Frontiers in Microbiology, 2024 - frontiersin.org
The development of antibiotic resistance compromises the effectiveness of our most effective
defenses against bacterial infections, presenting a threat to global health. To date, a large …

Risk factors in acquiring multidrug-resistant Klebsiella pneumoniae infections in a hospital setting in Saudi Arabia

ME Ibrahim - Scientific Reports, 2023 - nature.com
Over the last decades, the prevalence of multidrug-resistant (MDR) Klebsiella pneumoniae
in clinical settings has increased progressively. This study determined the prevalence and …

Resistance genomics and molecular epidemiology of high-risk clones of ESBL-producing Pseudomonas aeruginosa in young children

S Patil, X Chen, S Dong, H Mai, BS Lopes… - Frontiers in cellular …, 2023 - frontiersin.org
Introduction The emergence of multidrug-resistant Pseudomonas aeruginosa poses a global
threat, but the distribution and resistance profiling are unclear, especially in young children …

Epidemiology and antimicrobial resistance patterns of urinary tract infections: A cross-sectional study from Southwestern Saudi Arabia

AH Alhazmi, KM Alameer, BM Abuageelah, RH Alharbi… - Medicina, 2023 - mdpi.com
Background: Urinary tract infections (UTIs) are a prevalent form of urinary tract diseases
affecting individuals of all ages and genders. In the Kingdom of Saudi Arabia (KSA), UTIs …

Bacterial infections epidemiology and factors associated with multidrug resistance in the northern region of Ghana

JP Gnimatin, EW Weyori, SM Agossou, MN Adokiya - Scientific Reports, 2022 - nature.com
Bacterial infections caused by multidrug resistant organisms are a major global threat. There
is still a knowledge gap on this situation in the Northern Region of Ghana. This study …

[HTML][HTML] Evidence-based treatment of Pseudomonas aeruginosa infections: a critical reappraisal

A Karruli, C Catalini, C D'Amore, F Foglia, F Mari… - Antibiotics, 2023 - mdpi.com
Multidrug-resistant (MDR)/extensively drug-resistant (XDR) Pseudomonas aeruginosa is
emerging as a major threat related to adverse patient outcomes. The goal of this review is to …

[HTML][HTML] Assessment of risk factors associated with multidrug-resistant organism infections among patients admitted in a tertiary hospital-a retrospective study

AF Alsehemi, EA Alharbi, BB Alammash… - Saudi Pharmaceutical …, 2023 - Elsevier
Background Bacterial resistance has become a global health concern. To treat suspected
multidrug resistant organisms (MDROs), physicians first use broad-spectrum antibiotics; …

Combination of niclosamide and pirfenidone alleviates pulmonary fibrosis by inhibiting oxidative stress and MAPK/Nf-κB and STATs regulated genes

H Wanas, HM Elbadawy, MA Almikhlafi, AE Hamoud… - Pharmaceuticals, 2023 - mdpi.com
The pathogenesis of pulmonary fibrosis (PF) is extremely complex and involves numerous
intersecting pathways. The successful management of PF may require combining multiple …

[HTML][HTML] Donor respiratory multidrug-resistant bacteria and lung transplantation outcomes

R Abdulqawi, RA Saleh, RM Alameer, H Aldakhil… - Journal of Infection, 2024 - Elsevier
Rationale Respiratory culture screening is mandatory for all potential lung transplant donors.
There is limited evidence on the significance of donor multidrug-resistant (MDR) bacteria on …